ES8102132A1 - Un metodo para preparar sales de adicion cristalina de cefa-losporina - Google Patents
Un metodo para preparar sales de adicion cristalina de cefa-losporinaInfo
- Publication number
- ES8102132A1 ES8102132A1 ES491386A ES491386A ES8102132A1 ES 8102132 A1 ES8102132 A1 ES 8102132A1 ES 491386 A ES491386 A ES 491386A ES 491386 A ES491386 A ES 491386A ES 8102132 A1 ES8102132 A1 ES 8102132A1
- Authority
- ES
- Spain
- Prior art keywords
- losporina
- cefa
- preparing
- additional salts
- crystalline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- -1 cephalosporin salts Chemical class 0.000 abstract 2
- NEYLVMUGIIOTQK-SBXXRYSUSA-N (6R)-3-[[1-[2-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound NC=1SC=C(N=1)CC(=O)NC(CN1N=NN=C1SCC=1CS[C@H]2N(C=1C(=O)O)C(C2)=O)N(C)C NEYLVMUGIIOTQK-SBXXRYSUSA-N 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5948179A JPS55151588A (en) | 1979-05-14 | 1979-05-14 | Preparation of cephalosporin salt crystal |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8102132A1 true ES8102132A1 (es) | 1980-12-16 |
| ES491386A0 ES491386A0 (es) | 1980-12-16 |
Family
ID=13114535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491386A Granted ES491386A0 (es) | 1979-05-14 | 1980-05-12 | Un metodo para preparar sales de adicion cristalina de cefa-losporina |
Country Status (20)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR78221B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1980-02-01 | 1984-09-26 | Ciba Geigy Ag | |
| US4616008A (en) * | 1984-05-02 | 1986-10-07 | Takeda Chemical Industries, Ltd. | Antibacterial solid composition for oral administration |
| US5244891A (en) * | 1985-08-05 | 1993-09-14 | Bristol-Myers Squibb Company | Injectable compositions of cefepime dihydrochloride hydrate |
| CA1284994C (en) * | 1985-08-05 | 1991-06-18 | Murray Arthur Kaplan | Cephalosporin salts and injectable compositions |
| US4910301A (en) * | 1985-08-05 | 1990-03-20 | Bristol-Myers Company | Cefepime cephalosporin salts |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS603314B2 (ja) * | 1976-08-31 | 1985-01-26 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
| US4189479A (en) * | 1977-12-22 | 1980-02-19 | Takeda Chemical Industries, Ltd. | Cephalosporin esters |
-
1979
- 1979-05-14 JP JP5948179A patent/JPS55151588A/ja active Pending
-
1980
- 1980-05-03 GR GR61865A patent/GR68203B/el unknown
- 1980-05-06 NZ NZ193634A patent/NZ193634A/xx unknown
- 1980-05-06 US US06/147,053 patent/US4316018A/en not_active Expired - Lifetime
- 1980-05-12 SE SE8003548A patent/SE8003548L/ not_active Application Discontinuation
- 1980-05-12 ES ES491386A patent/ES491386A0/es active Granted
- 1980-05-13 GB GB8015741A patent/GB2052483A/en not_active Withdrawn
- 1980-05-13 NO NO801428A patent/NO801428L/no unknown
- 1980-05-13 DK DK209380A patent/DK209380A/da unknown
- 1980-05-13 IT IT22020/80A patent/IT1132053B/it active
- 1980-05-13 DE DE19803018340 patent/DE3018340A1/de not_active Withdrawn
- 1980-05-13 BE BE1/9820A patent/BE883250A/fr unknown
- 1980-05-13 NL NL8002758A patent/NL8002758A/nl not_active Application Discontinuation
- 1980-05-14 PT PT71241A patent/PT71241B/pt unknown
- 1980-05-14 AU AU58380/80A patent/AU5838080A/en not_active Abandoned
- 1980-05-14 SU SU802921250A patent/SU973024A3/ru active
- 1980-05-14 AT AT0259180A patent/AT367427B/de not_active IP Right Cessation
- 1980-05-14 FI FI801563A patent/FI801563A7/fi not_active Application Discontinuation
- 1980-05-14 ZA ZA00802874A patent/ZA802874B/xx unknown
- 1980-05-14 FR FR8010921A patent/FR2456746A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU5838080A (en) | 1980-11-20 |
| IT1132053B (it) | 1986-06-25 |
| ZA802874B (en) | 1980-12-31 |
| US4316018A (en) | 1982-02-16 |
| FR2456746A1 (fr) | 1980-12-12 |
| GB2052483A (en) | 1981-01-28 |
| GR68203B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-11-10 |
| PT71241B (en) | 1982-06-08 |
| ES491386A0 (es) | 1980-12-16 |
| PT71241A (en) | 1980-06-01 |
| NL8002758A (nl) | 1980-11-18 |
| IT8022020A0 (it) | 1980-05-13 |
| DK209380A (da) | 1980-11-15 |
| SE8003548L (sv) | 1980-11-15 |
| SU973024A3 (ru) | 1982-11-07 |
| AT367427B (de) | 1982-07-12 |
| ATA259180A (de) | 1981-11-15 |
| DE3018340A1 (de) | 1980-11-27 |
| NZ193634A (en) | 1982-05-25 |
| BE883250A (fr) | 1980-11-13 |
| FI801563A7 (fi) | 1980-11-15 |
| JPS55151588A (en) | 1980-11-26 |
| NO801428L (no) | 1980-11-17 |
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