ES507191A0 - Un procedimiento para la produccion de compuestos de fermen-tacion hipocolesterolemicos. - Google Patents

Un procedimiento para la produccion de compuestos de fermen-tacion hipocolesterolemicos.

Info

Publication number
ES507191A0
ES507191A0 ES507191A ES507191A ES507191A0 ES 507191 A0 ES507191 A0 ES 507191A0 ES 507191 A ES507191 A ES 507191A ES 507191 A ES507191 A ES 507191A ES 507191 A0 ES507191 A0 ES 507191A0
Authority
ES
Spain
Prior art keywords
compounds
hypocholesterolemic
fermention
procedure
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES507191A
Other languages
English (en)
Spanish (es)
Other versions
ES8302091A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES8302091A1 publication Critical patent/ES8302091A1/es
Publication of ES507191A0 publication Critical patent/ES507191A0/es
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/80Penicillium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES507191A 1980-11-17 1981-11-16 Un procedimiento para la produccion de compuestos de fermen-tacion hipocolesterolemicos. Granted ES507191A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/207,508 US4343814A (en) 1980-11-17 1980-11-17 Hypocholesterolemic fermentation products

Publications (2)

Publication Number Publication Date
ES8302091A1 ES8302091A1 (es) 1983-01-01
ES507191A0 true ES507191A0 (es) 1983-01-01

Family

ID=22770879

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507191A Granted ES507191A0 (es) 1980-11-17 1981-11-16 Un procedimiento para la produccion de compuestos de fermen-tacion hipocolesterolemicos.

Country Status (10)

Country Link
US (1) US4343814A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0052366B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS57122076A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE8244T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3164608D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK507781A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES507191A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR76327B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE52159B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT73964B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444784A (en) * 1980-08-05 1984-04-24 Merck & Co., Inc. Antihypercholesterolemic compounds
JPS57144279A (en) * 1981-03-02 1982-09-06 Sankyo Co Ltd Dihydro ml-236b and dihydro mb-530b and derivative thereof
US4503072A (en) * 1982-12-22 1985-03-05 Merck & Co., Inc. Antihypercholesterolemic compounds
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
CA1327360C (en) * 1983-11-14 1994-03-01 William F. Hoffman Oxo-analogs of mevinolin-like antihypercholesterolemic agents
US5208258A (en) * 1985-10-11 1993-05-04 The Regents Of The University Of California Antihypercholesterolemic compounds and synthesis thereof
US4950775A (en) * 1985-10-11 1990-08-21 University Of California Antihypercholesterolemic compounds and synthesis thereof
US5089523A (en) * 1990-05-11 1992-02-18 E. R. Squibb & Sons, Inc. Fluorinated derivatives of mevinic acids
BR0210426A (pt) 2001-06-13 2004-08-17 Ranbaxy Lab Ltd Metil análogo de sinvastatina para inibição de hmg-coa redutase e processo de obtenção do mesmo
ES2719689T3 (es) 2013-11-11 2019-07-12 Basf Se Cepas antifúngicas de penicillium, extrolitos fungicidas de las mismas y su uso

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1974-06-07 1981-03-18
US4049495A (en) * 1974-06-07 1977-09-20 Sankyo Company Limited Physiologically active substances and fermentative process for producing the same
US4137322A (en) * 1976-11-02 1979-01-30 Sankyo Company Limited ML-236B carboxylic acid derivatives and their use as antihyperlipemic agents
JPS55150898A (en) * 1979-05-11 1980-11-25 Sankyo Co Ltd Preparation of a new physiologically active substance mb-530b
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4294846A (en) * 1979-09-21 1981-10-13 Merck & Co., Inc. Hypocholesteremic fermentation products and products of preparation
US4282155A (en) * 1980-02-04 1981-08-04 Merck & Co., Inc. Antihypercholesterolemic compounds
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives

Also Published As

Publication number Publication date
DK507781A (da) 1982-05-18
ES8302091A1 (es) 1983-01-01
JPS57122076A (en) 1982-07-29
PT73964B (en) 1984-08-01
EP0052366A1 (en) 1982-05-26
GR76327B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-08-04
ATE8244T1 (de) 1984-07-15
JPH046189B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-02-05
US4343814A (en) 1982-08-10
DE3164608D1 (en) 1984-08-09
IE812671L (en) 1982-05-17
EP0052366B1 (en) 1984-07-04
IE52159B1 (en) 1987-07-22
PT73964A (en) 1981-12-01

Similar Documents

Publication Publication Date Title
ES8105389A1 (es) Un procedimiento de produccion de productos de fermentacion hipocolesteremicos.
ES482596A1 (es) Procedimiento para resolver mezclas de acidos (+)-y(-)-6- metoxi-alfa-metil-2-maftalenoaceticos.
SE7506498L (sv) Forfarande for framstellning av fysiologiskt aktiva substanster.
KR910700228A (ko) 알디미노-또는 케티미노-옥시-오르토-톨릴아크릴산의 메틸 에스테르, 이의 제조방법 및 이를 함유하는 살진균제
ES2063093T3 (es) Composiciones orales.
ES507191A0 (es) Un procedimiento para la produccion de compuestos de fermen-tacion hipocolesterolemicos.
FR2440376A1 (fr) Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
DK453386A (da) Farmaceutisk praeparat indeholdende 2-(2-fluor-4-bifenylyl)-propionsyre eller et farmaceutisk acceptabelt salt deraf
SE8005890L (sv) Salter av (+)-katekin, deras framstellning och anvendning, och kompositioner innehallande dessa salter
MX5937E (es) Procedimiento para la produccion de una biomasa bacteriostatica a partir de cepas de beggiatoa
GB1180873A (en) Amino-Esters of Substituted 4-Pentynoic-2-Acid, their Salification products and their method of manufacture
ES8501363A1 (es) Procedimientos de obtencion de amidoaminoacidos y similares.
FR2409307A1 (fr) Procede de production de l'antibiotique c-15003 p-3 par culture d'un micro-organisme
SE7905659L (sv) Medel for behandling av seborreiska tillstand
FR2458533B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU555784B2 (en) Preparation of (d) 2-(6-methoxy-2-naphthyl) propionic acid
SE7904319L (sv) Substituerade dibensyletrar samt forfarande for framstellning av dem
NO150240C (no) 4-(2`,2`,2`-trihalogenetyl)cyklobutan-1-sulfonsyresalter
BG93515A (bg) Тиазолил-5-карбонамидни производни и средство за борба срещу вредители по растенията
FR2355506A1 (fr) Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation
SE8001617L (sv) Forfarande for framstellning av ett karbazolderivat
FR2319709A1 (fr) Milieu, notamment pour la constitution de milieux de culture de micro-organismes
JPS5692786A (en) Cultivation of microorganism
FR2429773A1 (fr) Nouveau derive de l'acide acetylsalicylique, procede d'obtention de celui-ci et composition pharmaceutique en comportant application
JPS5359646A (en) Novel process for preparation of insecticides