ES488705A1 - Procedimiento para la preparacion de endo-aril-exo-pirrolin-amidinas - Google Patents

Procedimiento para la preparacion de endo-aril-exo-pirrolin-amidinas

Info

Publication number
ES488705A1
ES488705A1 ES488705A ES488705A ES488705A1 ES 488705 A1 ES488705 A1 ES 488705A1 ES 488705 A ES488705 A ES 488705A ES 488705 A ES488705 A ES 488705A ES 488705 A1 ES488705 A1 ES 488705A1
Authority
ES
Spain
Prior art keywords
alkoxy
substituted
nitrogen atom
hydrogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES488705A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES488705A1 publication Critical patent/ES488705A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/05Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems

Abstract

Procedimiento para la preparación de endo-aril-exo-pirrolin- amidinas de la fórmula XVII **(Fórmula)** y de sus sales fisiológicamente compatibles, donde a) n es 1 ó 2; b) R1 y R2 son hidrógeno o radicales alcohilo, que en común con el átomo de nitrógeno pueden formar un anillo de 5, 6, ó 7 miembros, el cual puede estar substituido con grupos alcohilo de 1 a 3 átomos de carbono, alcoxi de 1 a 2 átomos de carbono, hidroxi o alcoxicarbonilo de 1 a 4 átomos de carbono, y donde uno de los átomos de carbono puede estar reemplazado también por un átomo de oxígeno, azufre o nitrógeno, pudiendo estar substituido el átomo de nitrógeno con hidrógeno, con el grupo formilo, o con un radical fenilo.
ES488705A 1979-02-23 1980-02-18 Procedimiento para la preparacion de endo-aril-exo-pirrolin-amidinas Expired ES488705A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792907070 DE2907070A1 (de) 1979-02-23 1979-02-23 Heterocyclische spiroverknuepfte amidine und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES488705A1 true ES488705A1 (es) 1980-09-16

Family

ID=6063739

Family Applications (5)

Application Number Title Priority Date Filing Date
ES488702A Expired ES488702A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488706A Expired ES488706A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de isomeros opticos de amidinas heterociclicas de condensacion espiro
ES488704A Expired ES488704A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488703A Expired ES488703A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488705A Expired ES488705A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de endo-aril-exo-pirrolin-amidinas

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES488702A Expired ES488702A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488706A Expired ES488706A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de isomeros opticos de amidinas heterociclicas de condensacion espiro
ES488704A Expired ES488704A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488703A Expired ES488703A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro

Country Status (11)

Country Link
US (1) US4277470A (es)
EP (1) EP0014996B1 (es)
JP (1) JPS55120563A (es)
AT (1) ATE914T1 (es)
AU (1) AU534240B2 (es)
CA (1) CA1140930A (es)
DE (2) DE2907070A1 (es)
DK (1) DK77280A (es)
ES (5) ES488702A1 (es)
IL (1) IL59441A0 (es)
ZA (1) ZA801041B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
SE9904121D0 (sv) 1999-11-15 1999-11-15 Gustaf Jederstroem Hydrophobe biomolecular structure

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2911409A (en) * 1955-07-18 1959-11-03 Upjohn Co 2-spiro-substituted pyrrolidines
US2931805A (en) * 1958-11-10 1960-04-05 Smith Kline French Lab Spiro [bicyclo [2. 2. 1] heptane-2, 2'-alkylenimines]

Also Published As

Publication number Publication date
EP0014996B1 (de) 1982-04-28
DE3060314D1 (en) 1982-06-09
CA1140930A (en) 1983-02-08
ES488706A1 (es) 1980-09-16
ES488702A1 (es) 1980-09-16
ATE914T1 (de) 1982-05-15
US4277470A (en) 1981-07-07
AU534240B2 (en) 1984-01-12
DE2907070A1 (de) 1980-09-04
ES488704A1 (es) 1980-09-16
DK77280A (da) 1980-08-24
ZA801041B (en) 1981-03-25
ES488703A1 (es) 1980-09-16
JPS55120563A (en) 1980-09-17
IL59441A0 (en) 1980-05-30
AU5580680A (en) 1980-08-28
EP0014996A1 (de) 1980-09-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601