ES485554A0 - Un procedimiento para la preparacion de derivados de 5-fluoruracilo - Google Patents
Un procedimiento para la preparacion de derivados de 5-fluoruraciloInfo
- Publication number
- ES485554A0 ES485554A0 ES485554A ES485554A ES485554A0 ES 485554 A0 ES485554 A0 ES 485554A0 ES 485554 A ES485554 A ES 485554A ES 485554 A ES485554 A ES 485554A ES 485554 A0 ES485554 A0 ES 485554A0
- Authority
- ES
- Spain
- Prior art keywords
- fluoruracil
- derivatives
- procedure
- preparation
- fluoruracil derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7842426 | 1978-10-30 | ||
| GB7909522 | 1979-03-19 | ||
| GB7919439 | 1979-06-04 | ||
| GB8002195 | 1980-01-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES485554A0 true ES485554A0 (es) | 1980-11-01 |
| ES8100275A1 ES8100275A1 (es) | 1980-11-01 |
Family
ID=27449090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES485554A Expired ES8100275A1 (es) | 1978-10-30 | 1979-10-30 | Un procedimiento para la preparacion de derivados de 5-fluoruracilo |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0010941B1 (es) |
| DE (1) | DE2962834D1 (es) |
| ES (1) | ES8100275A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2539412B1 (fr) * | 1983-01-13 | 1986-02-21 | Shoichiro Ozaki | Derives du 5-fluoruracile et leurs utilisations therapeutiques en tant qu'agents carcinostatiques |
| IL73840A (en) * | 1983-12-19 | 1988-11-15 | Uniroyal Chem Co Inc | 2-thio-5-(thio)carbamoyl barbituric acid derivatives,their preparation and pharmaceutical compositions containing them |
| JPS61204172A (ja) * | 1985-03-07 | 1986-09-10 | Nippon Kayaku Co Ltd | ５−フルオロウラシル誘導体 |
| DE3781357T2 (de) * | 1986-10-09 | 1993-03-18 | Daikin Ind Ltd | 5-fluorouracil-derivate, pharmazeutische zubereitung und verwendung. |
| EP1939186A1 (en) * | 2006-12-22 | 2008-07-02 | Sulfidris S.r.l. | 5-Fluorouracil derivatives and their use for the treatment of cancer |
| CN109384730B (zh) * | 2017-08-10 | 2022-02-18 | 南京友怡医药科技有限公司 | 1-{3-[对-双-(2-氯乙基)胺基]苯丙胺基}甲酰-5-氟脲嘧啶及制备和应用 |
| CN115850190B (zh) * | 2023-01-10 | 2024-09-10 | 四川大学 | 一种5-氟尿嘧啶衍生物及其抗肿瘤用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5324952B2 (es) * | 1973-11-28 | 1978-07-24 | ||
| JPS5285179A (en) * | 1976-01-08 | 1977-07-15 | Mitsui Toatsu Chem Inc | Preparation of carbamoylated 5-fluorouracils |
-
1979
- 1979-10-29 EP EP19790302358 patent/EP0010941B1/en not_active Expired
- 1979-10-29 DE DE7979302358T patent/DE2962834D1/de not_active Expired
- 1979-10-30 ES ES485554A patent/ES8100275A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0010941B1 (en) | 1982-05-12 |
| DE2962834D1 (en) | 1982-07-01 |
| EP0010941A1 (en) | 1980-05-14 |
| ES8100275A1 (es) | 1980-11-01 |
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