ES482128A1 - Procedimiento para la preparacion de nuevos derivados de prostaglandina. - Google Patents
Procedimiento para la preparacion de nuevos derivados de prostaglandina.Info
- Publication number
- ES482128A1 ES482128A1 ES482128A ES482128A ES482128A1 ES 482128 A1 ES482128 A1 ES 482128A1 ES 482128 A ES482128 A ES 482128A ES 482128 A ES482128 A ES 482128A ES 482128 A1 ES482128 A1 ES 482128A1
- Authority
- ES
- Spain
- Prior art keywords
- medicaments
- delta
- preparation
- denotes
- straight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Prostaglandin compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000003180 prostaglandins Chemical class 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000027119 gastric acid secretion Effects 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
- 230000002408 ulcerprotective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5428—Acyclic unsaturated phosphonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
Las prostaglandinas son un grupo de ácidos grasos, que se presentan en numerosos tejidos y órganos de hombres y animales. La estructura fundamental de las prostaglandinas naturales consta de 20 átomos de carbono, que están dispuestos en forma de un anillo de cinco miembros y de dos cadenas laterales lineales contiguas. Los efectos farmacológicos de las prostaglandinas se extienden, entre otras cosas, a los sectores de la reproducción, del tono muscular bronquial, de la presión sanguínea y de la gastroenterología. Las propiedades farmacológicas de las prostaglandinas naturales son objeto de numerosos artículos sinópticos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782830079 DE2830079A1 (de) | 1978-07-08 | 1978-07-08 | Neue prostaglandinderivate der delta 2,4-11-desoxy-pge-reihe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES482128A1 true ES482128A1 (es) | 1980-08-16 |
Family
ID=6043884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES482128A Expired ES482128A1 (es) | 1978-07-08 | 1979-07-03 | Procedimiento para la preparacion de nuevos derivados de prostaglandina. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4258057A (es) |
| EP (1) | EP0007490B1 (es) |
| JP (1) | JPS5536470A (es) |
| AT (1) | ATE720T1 (es) |
| AU (1) | AU531714B2 (es) |
| CA (1) | CA1156226A (es) |
| DE (2) | DE2830079A1 (es) |
| ES (1) | ES482128A1 (es) |
| IL (1) | IL57738A (es) |
| ZA (1) | ZA793388B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552898A (en) * | 1982-07-14 | 1985-11-12 | Syntex (U.S.A.) Inc. | [3.2.0]Bicycloheptanone oxime ethers with valuable therapeutic properties |
| JPS63131366U (es) * | 1987-02-20 | 1988-08-26 | ||
| IN167720B (es) * | 1987-10-02 | 1990-12-08 | Tsuneyoshi Kawate | |
| US7314953B2 (en) * | 2001-03-27 | 2008-01-01 | Errant Gene Therapeutics, Llc | Treatment of lung cells with histone deacetylase inhibitors |
| US8026280B2 (en) | 2001-03-27 | 2011-09-27 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US6495719B2 (en) * | 2001-03-27 | 2002-12-17 | Circagen Pharmaceutical | Histone deacetylase inhibitors |
| US7312247B2 (en) | 2001-03-27 | 2007-12-25 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US7842727B2 (en) * | 2001-03-27 | 2010-11-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US20030108512A1 (en) * | 2001-12-10 | 2003-06-12 | Robert Shorr | Modified prostaglandin compounds and analogs thereof, compositions containing the same useful for the treatment of cancer |
| CA2486303C (en) * | 2002-05-22 | 2013-04-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors based on alpha-ketoepoxide compounds |
| CA2587013A1 (en) * | 2004-11-08 | 2006-05-18 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1414383A (en) * | 1972-11-14 | 1975-11-19 | Syntex Corp | Prostatrienoic acid derivatives and process |
| DE2460285A1 (de) * | 1973-12-25 | 1975-07-03 | Ono Pharmaceutical Co | Trans-delta hoch 2-prostaglandinverbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| US4098815A (en) * | 1974-02-15 | 1978-07-04 | Hoechst Aktiengesellschaft | Novel analogues of prostanoic acids not occurring in nature |
| US4165437A (en) * | 1976-03-12 | 1979-08-21 | Ono Pharmaceutical Company, Ltd. | Δ3 -Prostaglandin analogs |
| US4061670A (en) * | 1976-07-19 | 1977-12-06 | American Cyanamid Company | 15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners |
-
1978
- 1978-07-08 DE DE19782830079 patent/DE2830079A1/de not_active Withdrawn
-
1979
- 1979-07-03 ES ES482128A patent/ES482128A1/es not_active Expired
- 1979-07-05 AT AT79102292T patent/ATE720T1/de not_active IP Right Cessation
- 1979-07-05 DE DE7979102292T patent/DE2962192D1/de not_active Expired
- 1979-07-05 EP EP79102292A patent/EP0007490B1/de not_active Expired
- 1979-07-05 US US06/054,874 patent/US4258057A/en not_active Expired - Lifetime
- 1979-07-06 ZA ZA793388A patent/ZA793388B/xx unknown
- 1979-07-06 AU AU48714/79A patent/AU531714B2/en not_active Ceased
- 1979-07-06 JP JP8512479A patent/JPS5536470A/ja active Pending
- 1979-07-06 IL IL57738A patent/IL57738A/xx unknown
- 1979-07-06 CA CA000331330A patent/CA1156226A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1156226A (en) | 1983-11-01 |
| EP0007490A2 (de) | 1980-02-06 |
| US4258057A (en) | 1981-03-24 |
| ZA793388B (en) | 1980-06-25 |
| JPS5536470A (en) | 1980-03-14 |
| AU531714B2 (en) | 1983-09-01 |
| EP0007490B1 (de) | 1982-02-24 |
| IL57738A (en) | 1983-05-15 |
| AU4871479A (en) | 1980-01-17 |
| IL57738A0 (en) | 1979-11-30 |
| DE2962192D1 (en) | 1982-03-25 |
| DE2830079A1 (de) | 1980-01-17 |
| EP0007490A3 (en) | 1980-05-14 |
| ATE720T1 (de) | 1982-03-15 |
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