ES479537A1 - Benzylidene esters - Google Patents
Benzylidene estersInfo
- Publication number
- ES479537A1 ES479537A1 ES479537A ES479537A ES479537A1 ES 479537 A1 ES479537 A1 ES 479537A1 ES 479537 A ES479537 A ES 479537A ES 479537 A ES479537 A ES 479537A ES 479537 A1 ES479537 A1 ES 479537A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- esters
- carbon atoms
- alkyl
- benzylidene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
Abstract
Bensylidene esters corresponding to the formula (I> < IMAGE > in which X1, X2 and X3, which are identical or different, each represent a hydrogen or halogen or a methyl or methoxy radical, n = 1 to 10 and R represents an alkyl radical having 1 to 16 carbon atoms, a radical CH2COOR1 in which R1 is a higher alkyl having 11 to 15 carbon atoms, a radical (CH2)2OR2 in which R2 is an alkyl having 1 to 6 carbon atoms, or a radical < IMAGE > The esters are anti-convulsants and are useful in treating disorders of the central nervous system. Processes for preparing them and pharmaceutical preparations containing them are also claimed.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7811025A FR2422628A1 (en) | 1978-04-14 | 1978-04-14 | BENZYLIDENIC ESTERS AND THEIR APPLICATION IN THERAPEUTICS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES479537A1 true ES479537A1 (en) | 1979-11-01 |
Family
ID=9207131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES479537A Expired ES479537A1 (en) | 1978-04-14 | 1979-04-11 | Benzylidene esters |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS54138548A (en) |
| AU (1) | AU4590979A (en) |
| BE (1) | BE875588A (en) |
| DE (1) | DE2914801A1 (en) |
| DK (1) | DK149179A (en) |
| ES (1) | ES479537A1 (en) |
| FI (1) | FI791186A (en) |
| FR (1) | FR2422628A1 (en) |
| GB (1) | GB2018755A (en) |
| IL (1) | IL57060A0 (en) |
| IT (1) | IT1111922B (en) |
| LU (1) | LU81146A1 (en) |
| NL (1) | NL7902952A (en) |
| NO (1) | NO791221L (en) |
| PT (1) | PT69486A (en) |
| SE (1) | SE7903233L (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0047516B1 (en) * | 1980-09-04 | 1984-01-04 | Toray Industries, Inc. | Propylamine derivative and process of manufacturing the same |
| JPS5746951A (en) * | 1980-09-04 | 1982-03-17 | Toray Ind Inc | Production of 2-amino-4-cyanobutyric derivative |
| FR2536746A1 (en) * | 1982-11-29 | 1984-06-01 | Synthelabo | ALKYL BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
-
1978
- 1978-04-14 FR FR7811025A patent/FR2422628A1/en active Granted
-
1979
- 1979-04-10 DK DK149179A patent/DK149179A/en not_active IP Right Cessation
- 1979-04-10 AU AU45909/79A patent/AU4590979A/en not_active Abandoned
- 1979-04-10 NO NO791221A patent/NO791221L/en unknown
- 1979-04-11 FI FI791186A patent/FI791186A/en not_active Application Discontinuation
- 1979-04-11 SE SE7903233A patent/SE7903233L/en unknown
- 1979-04-11 DE DE19792914801 patent/DE2914801A1/en not_active Withdrawn
- 1979-04-11 ES ES479537A patent/ES479537A1/en not_active Expired
- 1979-04-11 IL IL57060A patent/IL57060A0/en unknown
- 1979-04-11 IT IT21794/79A patent/IT1111922B/en active
- 1979-04-12 PT PT69486A patent/PT69486A/en unknown
- 1979-04-12 NL NL7902952A patent/NL7902952A/en not_active Application Discontinuation
- 1979-04-12 GB GB7912933A patent/GB2018755A/en not_active Withdrawn
- 1979-04-12 LU LU81146A patent/LU81146A1/en unknown
- 1979-04-13 BE BE0/194613A patent/BE875588A/en unknown
- 1979-04-13 JP JP4595679A patent/JPS54138548A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SE7903233L (en) | 1979-10-15 |
| NL7902952A (en) | 1979-10-16 |
| IT7921794A0 (en) | 1979-04-11 |
| NO791221L (en) | 1979-10-16 |
| LU81146A1 (en) | 1980-12-16 |
| DE2914801A1 (en) | 1979-10-18 |
| IL57060A0 (en) | 1979-07-25 |
| FR2422628B1 (en) | 1980-10-03 |
| DK149179A (en) | 1979-10-15 |
| JPS54138548A (en) | 1979-10-27 |
| IT1111922B (en) | 1986-01-13 |
| FR2422628A1 (en) | 1979-11-09 |
| BE875588A (en) | 1979-10-15 |
| AU4590979A (en) | 1979-10-18 |
| GB2018755A (en) | 1979-10-24 |
| PT69486A (en) | 1979-05-01 |
| FI791186A (en) | 1979-10-15 |
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