ES477954A1 - A procedure for preparing a 17a-chlorine-17b- (m-sulfinil) -1,4-androstadien-3-ona. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparing a 17a-chlorine-17b- (m-sulfinil) -1,4-androstadien-3-ona. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES477954A1
ES477954A1 ES477954A ES477954A ES477954A1 ES 477954 A1 ES477954 A1 ES 477954A1 ES 477954 A ES477954 A ES 477954A ES 477954 A ES477954 A ES 477954A ES 477954 A1 ES477954 A1 ES 477954A1
Authority
ES
Spain
Prior art keywords
androstadien
translation
preparing
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES477954A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/881,217 external-priority patent/US4183924A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of ES477954A1 publication Critical patent/ES477954A1/en
Expired legal-status Critical Current

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Abstract

1. A process for preparing a 17 alpha-chloro 17 beta- (m-sulfinyl) -1,4-androstadien-3-one having the following partial formula at c-17: ** (formula 01) ** where m is a benzyl, phenethyl, methylbenzyl, dimethylbenzyl, chlorobenzyl or dichlorobenzyl group or an alkyl group having 1 to 8 carbon atoms, characterized in that a 17alpha- (m-thio) -1,4-androstadiene is reacted -3-one, which has the following partial formula in c-17: ** (formula 02) ** where m is in accordance with that defined above, with a chlorine source in a solvent system comprising water, and a water-soluble base, at a temperature of about -78 to about 25 degrees centigrade. (Machine-translation by Google Translate, not legally binding)
ES477954A 1978-02-27 1979-02-22 A procedure for preparing a 17a-chlorine-17b- (m-sulfinil) -1,4-androstadien-3-ona. (Machine-translation by Google Translate, not legally binding) Expired ES477954A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/881,217 US4183924A (en) 1978-02-27 1978-02-27 17α-Chloro-17β-hydrocarbonsulfinyl-1,4-androstadienes and the corresponding 17β-hydrocarbonsulfonyl derivatives and their use as anti-acne agents
ZA79756A ZA79756B (en) 1978-02-27 1979-02-19 Novel androstadienes,their preparation and their use as dermatological agents

Publications (1)

Publication Number Publication Date
ES477954A1 true ES477954A1 (en) 1980-06-16

Family

ID=27128612

Family Applications (1)

Application Number Title Priority Date Filing Date
ES477954A Expired ES477954A1 (en) 1978-02-27 1979-02-22 A procedure for preparing a 17a-chlorine-17b- (m-sulfinil) -1,4-androstadien-3-ona. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES477954A1 (en)

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