ES477300A1 - Procedimiento para la preparacion de bencenosulfonilureas. - Google Patents
Procedimiento para la preparacion de bencenosulfonilureas.Info
- Publication number
- ES477300A1 ES477300A1 ES477300A ES477300A ES477300A1 ES 477300 A1 ES477300 A1 ES 477300A1 ES 477300 A ES477300 A ES 477300A ES 477300 A ES477300 A ES 477300A ES 477300 A1 ES477300 A1 ES 477300A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- preparation
- benzenosulfonilureas
- procedure
- alkylcycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- -1 cyclohexenylmethyl Chemical group 0.000 abstract 3
- 125000005119 alkyl cycloalkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- QYCGBAJADAGLLK-UHFFFAOYSA-N 1-(cyclohepten-1-yl)cycloheptene Chemical group C1CCCCC=C1C1=CCCCCC1 QYCGBAJADAGLLK-UHFFFAOYSA-N 0.000 abstract 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- ARUKYTASOALXFG-UHFFFAOYSA-N cycloheptylcycloheptane Chemical group C1CCCCCC1C1CCCCCC1 ARUKYTASOALXFG-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Procedimiento para la preparación de bencenosulfonilureas de la fórmula **(Fórmula)** en la que R1 significa alcohilo con 3 a 8 átomos de carbono, cicloalcohilo, cicloalcohilalhilo, alcohilcicloalcohiloen cada caso con 5 a 9 átomos de carbono, fenilo, X, X1 significan hidrógeno, alcohilo con hasta 4 átomos de carbono, halógeno, Y significa alcohileno con 1 a 6 átomos de carbono, cicloalcohilo, alcohilcicloalcohilo, cicloalcohilalcohilo, cicloalquenilo, alcohilcicloalquenilo en cada caso con en total 5 a 9 átomos de carbono, alcohilciclopentilmetilo, ciclohexenilmetilo, clorociclohexilo, bicicloheptenilmetilo, bicicloheptilmetilo, bicicloheptenilo, bicicloheptilo, nortriciclilo, adamantilo, bencilo, y sus sales fisiológicamente compatibles.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2720926A DE2720926C2 (de) | 1977-05-10 | 1977-05-10 | Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES477300A1 true ES477300A1 (es) | 1979-07-01 |
Family
ID=6008493
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469454A Expired ES469454A1 (es) | 1977-05-10 | 1978-05-04 | Procedimiento para la preparacion de bencenosulfonilureas |
| ES477300A Expired ES477300A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
| ES477302A Expired ES477302A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
| ES477301A Expired ES477301A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
| ES477303A Expired ES477303A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
| ES477304A Expired ES477304A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469454A Expired ES469454A1 (es) | 1977-05-10 | 1978-05-04 | Procedimiento para la preparacion de bencenosulfonilureas |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES477302A Expired ES477302A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
| ES477301A Expired ES477301A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
| ES477303A Expired ES477303A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
| ES477304A Expired ES477304A1 (es) | 1977-05-10 | 1979-01-31 | Procedimiento para la preparacion de bencenosulfonilureas. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4157395A (es) |
| JP (1) | JPS53141278A (es) |
| AT (1) | AT366366B (es) |
| BE (1) | BE866928A (es) |
| CH (1) | CH637119A5 (es) |
| DE (1) | DE2720926C2 (es) |
| DK (1) | DK203278A (es) |
| EG (1) | EG13856A (es) |
| ES (6) | ES469454A1 (es) |
| FI (1) | FI781451A7 (es) |
| FR (1) | FR2390432A1 (es) |
| GB (1) | GB1599250A (es) |
| HU (1) | HU178247B (es) |
| IE (1) | IE46824B1 (es) |
| IL (1) | IL54660A (es) |
| IT (1) | IT1094608B (es) |
| NL (1) | NL7804988A (es) |
| NO (1) | NO781637L (es) |
| NZ (1) | NZ187195A (es) |
| PH (1) | PH15602A (es) |
| PT (1) | PT68015B (es) |
| SE (1) | SE7805357L (es) |
| ZA (1) | ZA782629B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4260824A (en) * | 1979-09-21 | 1981-04-07 | Stauffer Chemical Company | Sulfonylurea herbicidal antidotes |
| US4365990A (en) * | 1979-09-21 | 1982-12-28 | Stauffer Chemical Company | Sulfonylurea herbicidal antidotes |
| IT1276130B1 (it) | 1995-11-14 | 1997-10-27 | Gentili Ist Spa | Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo |
| TR199902432T2 (xx) * | 1997-04-04 | 2000-01-21 | Prizer Products Inc. | Nikotinamid t�revleri. |
| EP1229034B1 (en) * | 2001-01-31 | 2005-04-13 | Pfizer Products Inc. | Nicotinamide derivatives and their mimetics as inhibitors of PDE4 isozymes |
| US7250518B2 (en) * | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4066639A (en) * | 1965-05-06 | 1978-01-03 | Hoechst Aktiengesellschaft | Benzene-sulfonyl semicarbazides and process for preparing them |
| JPS5133103B1 (es) * | 1971-04-05 | 1976-09-17 | ||
| US3879403A (en) * | 1973-05-04 | 1975-04-22 | Pfizer | Benzenesulfonylurea derivatives |
-
1977
- 1977-05-10 DE DE2720926A patent/DE2720926C2/de not_active Expired
-
1978
- 1978-05-04 ES ES469454A patent/ES469454A1/es not_active Expired
- 1978-05-08 US US05/903,548 patent/US4157395A/en not_active Expired - Lifetime
- 1978-05-08 FI FI781451A patent/FI781451A7/fi not_active Application Discontinuation
- 1978-05-08 IT IT23146/78A patent/IT1094608B/it active
- 1978-05-08 NZ NZ187195A patent/NZ187195A/xx unknown
- 1978-05-08 CH CH498878A patent/CH637119A5/de not_active IP Right Cessation
- 1978-05-08 EG EG293/78A patent/EG13856A/xx active
- 1978-05-08 IL IL54660A patent/IL54660A/xx unknown
- 1978-05-09 NO NO781637A patent/NO781637L/no unknown
- 1978-05-09 DK DK203278A patent/DK203278A/da not_active Application Discontinuation
- 1978-05-09 PT PT68015A patent/PT68015B/pt unknown
- 1978-05-09 AT AT0335478A patent/AT366366B/de not_active IP Right Cessation
- 1978-05-09 NL NL7804988A patent/NL7804988A/xx not_active Application Discontinuation
- 1978-05-09 GB GB18454/78A patent/GB1599250A/en not_active Expired
- 1978-05-09 IE IE941/78A patent/IE46824B1/en unknown
- 1978-05-09 ZA ZA00782629A patent/ZA782629B/xx unknown
- 1978-05-10 BE BE187577A patent/BE866928A/xx not_active IP Right Cessation
- 1978-05-10 PH PH21122A patent/PH15602A/en unknown
- 1978-05-10 JP JP5544478A patent/JPS53141278A/ja active Pending
- 1978-05-10 FR FR7813836A patent/FR2390432A1/fr active Granted
- 1978-05-10 SE SE7805357A patent/SE7805357L/xx unknown
- 1978-05-10 HU HU78HO2073A patent/HU178247B/hu unknown
-
1979
- 1979-01-31 ES ES477300A patent/ES477300A1/es not_active Expired
- 1979-01-31 ES ES477302A patent/ES477302A1/es not_active Expired
- 1979-01-31 ES ES477301A patent/ES477301A1/es not_active Expired
- 1979-01-31 ES ES477303A patent/ES477303A1/es not_active Expired
- 1979-01-31 ES ES477304A patent/ES477304A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1599250A (en) | 1981-09-30 |
| IL54660A (en) | 1981-11-30 |
| ES477302A1 (es) | 1979-07-01 |
| ZA782629B (en) | 1979-04-25 |
| ES477303A1 (es) | 1979-07-01 |
| AT366366B (de) | 1982-04-13 |
| FI781451A7 (fi) | 1978-11-11 |
| FR2390432A1 (fr) | 1978-12-08 |
| SE7805357L (sv) | 1978-11-11 |
| JPS53141278A (en) | 1978-12-08 |
| CH637119A5 (de) | 1983-07-15 |
| EG13856A (en) | 1982-06-30 |
| NO781637L (no) | 1978-11-13 |
| IE46824B1 (en) | 1983-10-05 |
| HU178247B (en) | 1982-04-28 |
| IL54660A0 (en) | 1978-07-31 |
| ATA335478A (de) | 1981-08-15 |
| NL7804988A (nl) | 1978-11-14 |
| DK203278A (da) | 1978-11-11 |
| IT7823146A0 (it) | 1978-05-08 |
| DE2720926A1 (de) | 1978-11-23 |
| ES477301A1 (es) | 1979-07-01 |
| NZ187195A (en) | 1980-09-12 |
| DE2720926C2 (de) | 1983-02-17 |
| ES477304A1 (es) | 1979-07-01 |
| ES469454A1 (es) | 1979-08-16 |
| IT1094608B (it) | 1985-08-02 |
| IE780941L (en) | 1978-11-10 |
| US4157395A (en) | 1979-06-05 |
| FR2390432B1 (es) | 1981-11-27 |
| PT68015B (de) | 1980-03-05 |
| PH15602A (en) | 1983-02-28 |
| PT68015A (de) | 1978-06-01 |
| BE866928A (fr) | 1978-11-10 |
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