ES477280A1 - Procedimiento para la obtencion de un diastereomero especi- fico de eritro-2-(2-aralquilamino-1-hidroxietil)-1,4-benzo- dioxanos. - Google Patents
Procedimiento para la obtencion de un diastereomero especi- fico de eritro-2-(2-aralquilamino-1-hidroxietil)-1,4-benzo- dioxanos.Info
- Publication number
- ES477280A1 ES477280A1 ES477280A ES477280A ES477280A1 ES 477280 A1 ES477280 A1 ES 477280A1 ES 477280 A ES477280 A ES 477280A ES 477280 A ES477280 A ES 477280A ES 477280 A1 ES477280 A1 ES 477280A1
- Authority
- ES
- Spain
- Prior art keywords
- benzodioxanes
- aminoethyl
- preparation
- pharmaceutical compositions
- optical isomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BIDRHBDWACXXJK-UHFFFAOYSA-N 2-(2,3-dihydro-1,4-benzodioxin-3-yl)ethanamine Chemical class C1=CC=C2OC(CCN)COC2=C1 BIDRHBDWACXXJK-UHFFFAOYSA-N 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000059 bradycardiac effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedimiento para la obtención de un diastereómero específico del eritro-2-(2-aralquilamino-1-hidroxietil)-1,4-benzodioxanos de fórmula general I *** ver imagen 01 donde cada uno de los símbolos X e Y significan hidrógeno, alquilo inferior, alcoxi inferior, halógeno o trifluormetilo, cada uno de los símbolos p y q que presenta el número entero 1 ó 2 y cada uno de los símbolos m y n significa el número entero 1 hasta 4, y sus sales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87345778A | 1978-01-30 | 1978-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES477280A1 true ES477280A1 (es) | 1979-10-16 |
Family
ID=25361674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES477280A Expired ES477280A1 (es) | 1978-01-30 | 1979-01-30 | Procedimiento para la obtencion de un diastereomero especi- fico de eritro-2-(2-aralquilamino-1-hidroxietil)-1,4-benzo- dioxanos. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0003359B1 (es) |
| JP (1) | JPS54112878A (es) |
| AT (1) | ATA63379A (es) |
| AU (1) | AU4375879A (es) |
| DD (1) | DD142051A5 (es) |
| DE (1) | DE2960137D1 (es) |
| DK (1) | DK36879A (es) |
| ES (1) | ES477280A1 (es) |
| FI (1) | FI790270A7 (es) |
| GB (1) | GB2013204A (es) |
| GR (1) | GR71689B (es) |
| IE (1) | IE790152L (es) |
| IL (1) | IL56528A0 (es) |
| NO (1) | NO790281L (es) |
| NZ (1) | NZ189503A (es) |
| PL (1) | PL213102A1 (es) |
| PT (1) | PT69146B (es) |
| ZA (2) | ZA786692B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI903052A7 (fi) * | 1987-12-18 | 1990-06-18 | Schering Corp | 1-metyyli-3-fenyylipropyyliamiinin erottamiseen hyödylliset menetelmät ja yhdisteet |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1038333A (en) * | 1963-02-13 | 1966-08-10 | Ici Ltd | Pharmaceutical compositions |
-
1978
- 1978-11-28 ZA ZA00786692A patent/ZA786692B/xx unknown
-
1979
- 1979-01-26 GB GB7902922A patent/GB2013204A/en not_active Withdrawn
- 1979-01-26 DE DE7979100225T patent/DE2960137D1/de not_active Expired
- 1979-01-26 FI FI790270A patent/FI790270A7/fi unknown
- 1979-01-26 EP EP79100225A patent/EP0003359B1/de not_active Expired
- 1979-01-29 DK DK36879A patent/DK36879A/da unknown
- 1979-01-29 AT AT0063379A patent/ATA63379A/de not_active IP Right Cessation
- 1979-01-29 DD DD79210688A patent/DD142051A5/de unknown
- 1979-01-29 IL IL56528A patent/IL56528A0/xx unknown
- 1979-01-29 GR GR58200A patent/GR71689B/el unknown
- 1979-01-29 PT PT69146A patent/PT69146B/pt unknown
- 1979-01-29 NZ NZ189503A patent/NZ189503A/xx unknown
- 1979-01-29 NO NO790281A patent/NO790281L/no unknown
- 1979-01-29 ZA ZA79364A patent/ZA79364B/xx unknown
- 1979-01-30 JP JP885179A patent/JPS54112878A/ja active Pending
- 1979-01-30 IE IE790152A patent/IE790152L/xx unknown
- 1979-01-30 ES ES477280A patent/ES477280A1/es not_active Expired
- 1979-01-30 AU AU43758/79A patent/AU4375879A/en not_active Abandoned
- 1979-01-30 PL PL21310279A patent/PL213102A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL56528A0 (en) | 1979-03-12 |
| DE2960137D1 (en) | 1981-03-26 |
| EP0003359B1 (de) | 1981-02-11 |
| PT69146A (de) | 1979-02-01 |
| ZA79364B (en) | 1980-01-30 |
| DK36879A (da) | 1979-07-31 |
| FI790270A7 (fi) | 1979-07-31 |
| GB2013204A (en) | 1979-08-08 |
| GR71689B (es) | 1983-06-21 |
| ATA63379A (de) | 1981-07-15 |
| DD142051A5 (de) | 1980-06-04 |
| NO790281L (no) | 1979-07-31 |
| ZA786692B (en) | 1979-11-28 |
| JPS54112878A (en) | 1979-09-04 |
| NZ189503A (en) | 1981-03-16 |
| IE790152L (en) | 1979-07-30 |
| PL213102A1 (es) | 1980-02-25 |
| PT69146B (pt) | 1981-06-11 |
| AU4375879A (en) | 1979-08-09 |
| EP0003359A1 (de) | 1979-08-08 |
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