ES476623A1 - Process for the Recovery of Heparin - Google Patents

Process for the Recovery of Heparin

Info

Publication number
ES476623A1
ES476623A1 ES476623A ES476623A ES476623A1 ES 476623 A1 ES476623 A1 ES 476623A1 ES 476623 A ES476623 A ES 476623A ES 476623 A ES476623 A ES 476623A ES 476623 A1 ES476623 A1 ES 476623A1
Authority
ES
Spain
Prior art keywords
heparin
recovered
sodium chloride
recovery
intestinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES476623A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES476623A1 publication Critical patent/ES476623A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Heparin is recovered from intestinal brine formed by treatment, with aqueous sodium chloride solution or solid sodium chloride in the presence of water, of animal intestines from which intestinal mucus has been removed. The heparin recovered is almost completely free of by-products, and heparin of good quality is obtained.
ES476623A 1978-01-06 1979-01-05 Process for the Recovery of Heparin Expired ES476623A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2800943A DE2800943C2 (en) 1978-01-06 1978-01-06 Use of intestinal brine to obtain pure heparin

Publications (1)

Publication Number Publication Date
ES476623A1 true ES476623A1 (en) 1979-05-16

Family

ID=6029250

Family Applications (1)

Application Number Title Priority Date Filing Date
ES476623A Expired ES476623A1 (en) 1978-01-06 1979-01-05 Process for the Recovery of Heparin

Country Status (26)

Country Link
JP (1) JPS5943042B2 (en)
AR (1) AR220734A1 (en)
AT (1) AT365073B (en)
AU (1) AU526459B2 (en)
BE (1) BE873327A (en)
BR (1) BR7900056A (en)
CA (1) CA1132904A (en)
CH (1) CH638818A5 (en)
CS (1) CS216189B2 (en)
DD (1) DD141311A5 (en)
DE (1) DE2800943C2 (en)
DK (1) DK163063C (en)
ES (1) ES476623A1 (en)
FI (1) FI65073C (en)
FR (1) FR2414055A1 (en)
GB (1) GB2012790B (en)
GR (1) GR72952B (en)
HU (1) HU179594B (en)
IT (1) IT1109918B (en)
LU (1) LU80755A1 (en)
NL (1) NL187070C (en)
PL (1) PL117279B3 (en)
RO (1) RO78606A (en)
SE (1) SE439109B (en)
YU (1) YU301878A (en)
ZA (1) ZA787305B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3265781D1 (en) * 1981-05-21 1985-10-03 Akzo Nv New anti-thromboticum based on polysacharides, method for its preparation and pharmaceutical compositions
CN103601821B (en) * 2013-11-15 2016-01-06 重庆三腾食品有限公司 A kind of enzymolysis processing method and corresponding heparin sodium working method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1156938B (en) * 1957-09-23 1963-11-07 Upjohn Company Eine Ges Nach D Method for obtaining heparin
GB889010A (en) * 1957-11-06 1962-02-07 Crinos Industria Farmaco A new heparin-like compound
DE2660052A1 (en) * 1976-11-12 1979-01-25 Schering Ag Pure anticoagulant heparin prodn. - using salt lakes obtd. from mucus-free animal intestines by sprinkling with salt
DE2652272C2 (en) * 1976-11-12 1979-02-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Process for the production of heparin

Also Published As

Publication number Publication date
IT1109918B (en) 1985-12-23
FR2414055B1 (en) 1985-04-19
FI65073C (en) 1984-03-12
IT7919085A0 (en) 1979-01-05
GR72952B (en) 1984-01-17
AU526459B2 (en) 1983-01-13
CH638818A5 (en) 1983-10-14
DE2800943A1 (en) 1979-07-12
ATA6879A (en) 1981-05-15
PL212596A1 (en) 1979-11-05
AT365073B (en) 1981-12-10
DK163063B (en) 1992-01-13
GB2012790B (en) 1983-03-30
CA1132904A (en) 1982-10-05
DK582878A (en) 1979-07-07
DK163063C (en) 1992-06-15
FR2414055A1 (en) 1979-08-03
FI65073B (en) 1983-11-30
RO78606A (en) 1982-06-25
SE7900077L (en) 1979-07-07
AR220734A1 (en) 1980-11-28
DD141311A5 (en) 1980-04-23
BE873327A (en) 1979-07-05
JPS5497693A (en) 1979-08-01
FI783904A (en) 1979-07-07
JPS5943042B2 (en) 1984-10-19
NL187070B (en) 1990-12-17
NL7812621A (en) 1979-07-10
DE2800943C2 (en) 1984-09-27
CS216189B2 (en) 1982-10-29
PL117279B3 (en) 1981-07-31
BR7900056A (en) 1979-08-14
NL187070C (en) 1991-05-16
ZA787305B (en) 1979-12-27
LU80755A1 (en) 1979-04-13
HU179594B (en) 1982-11-29
SE439109B (en) 1985-06-03
YU301878A (en) 1985-04-30
GB2012790A (en) 1979-08-01
AU4318179A (en) 1979-07-12

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