ES475533A1 - Novel propione amide derivative and its manufacture - Google Patents

Novel propione amide derivative and its manufacture

Info

Publication number
ES475533A1
ES475533A1 ES475533A ES475533A ES475533A1 ES 475533 A1 ES475533 A1 ES 475533A1 ES 475533 A ES475533 A ES 475533A ES 475533 A ES475533 A ES 475533A ES 475533 A1 ES475533 A1 ES 475533A1
Authority
ES
Spain
Prior art keywords
novel
manufacture
amide derivative
novel compounds
parenteral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES475533A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Menarini SAS
Original Assignee
Menarini SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini SAS filed Critical Menarini SAS
Publication of ES475533A1 publication Critical patent/ES475533A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Abstract

Novel compounds useful as spasmolytic agents of the following formula: < IMAGE > in which n is 2 or 3. In addition, salts of these novel compounds are provided which are suitable for parenteral and oral administration to animals and humans as spasmolytic agents. In compositions for oral and parenteral or rectal administration, about 5 to about 40 mg of active ingredient per dosage unit are used. The bromide and iodide salts of these novel compounds are particularly useful.
ES475533A 1977-11-30 1978-11-29 Novel propione amide derivative and its manufacture Expired ES475533A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT964377A IT1090782B (en) 1977-11-30 1977-11-30 2 4 BIPHENYLIL 2 DIETHYLAMIN ALCHYL PROPIONAMIDE ITS SALTS AND RELATED MANUFACTURING PROCEDURES

Publications (1)

Publication Number Publication Date
ES475533A1 true ES475533A1 (en) 1980-01-16

Family

ID=11132874

Family Applications (1)

Application Number Title Priority Date Filing Date
ES475533A Expired ES475533A1 (en) 1977-11-30 1978-11-29 Novel propione amide derivative and its manufacture

Country Status (9)

Country Link
JP (1) JPS5490157A (en)
BE (1) BE872403A (en)
CA (1) CA1118446A (en)
CH (1) CH637370A5 (en)
DE (1) DE2851416A1 (en)
ES (1) ES475533A1 (en)
FR (1) FR2410641A1 (en)
IT (1) IT1090782B (en)
NL (1) NL7811698A (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20012025A1 (en) * 2001-09-28 2003-03-28 Dompe Spa QUATERNARY AMMONIUM SALTS OF OMEGA-AMINO ALKYLAMIDS OF R 2-ARY-PROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
ES2559781T3 (en) * 2006-08-08 2016-02-15 Techfields Biochem Co. Ltd Prodrugs of water soluble and positively charged aryl- and heteroarylacetic acids with a very fast skin penetration rate
AU2013206218B2 (en) * 2006-08-15 2016-06-30 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
EP2054384A4 (en) * 2006-08-15 2010-11-03 Techfields Biochem Co Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
KR20150058566A (en) 2007-06-04 2015-05-28 테크필즈 인크 Pro-drugs of NSAIAs With Very High Skin and Membranes Penetration Rates and Their New Medicinal Uses
CN108191846B (en) 2008-12-04 2021-08-20 于崇曦 High penetration composition and application thereof
JP5940036B2 (en) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin permeability
JP6290947B2 (en) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin permeability

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584547A (en) * 1968-06-05 1969-12-26
FR1593024A (en) * 1968-09-18 1970-05-25
FR2119846A1 (en) * 1970-12-28 1972-08-11 Choay Sa N,n-diethylaminoethylamide of para isobutyl phenylacetic - acid - antiinflammatory and analgesic
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds

Also Published As

Publication number Publication date
DE2851416A1 (en) 1979-05-31
CH637370A5 (en) 1983-07-29
BE872403A (en) 1979-03-16
JPS631286B2 (en) 1988-01-12
NL7811698A (en) 1979-06-01
DE2851416C2 (en) 1989-02-23
JPS5490157A (en) 1979-07-17
FR2410641A1 (en) 1979-06-29
CA1118446A (en) 1982-02-16
FR2410641B1 (en) 1983-04-15
IT1090782B (en) 1985-06-26

Similar Documents

Publication Publication Date Title
ES485188A1 (en) Diphenylbutyl-piperzinecarboxamides
ES473451A1 (en) Imidazole derivatives their synthesis and their pharmaceutical formulations.
SE7614258L (en) PROCEDURE FOR THE PREPARATION OF CHINAZOLO DERIVATIVE
IL57648A (en) 2-substituted-5,9-dimethyl-2&#39;-hydroxy-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them
FR2361901A1 (en) NUCLEOTIDES SUBSTITUTION DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
NO301542B1 (en) New pyrazine derivatives
ES465527A1 (en) N-(phenylalkylamino-alkyl)-dihydroisoquinolinones, pharmaceutical compositions and methods employing them
ES475533A1 (en) Novel propione amide derivative and its manufacture
ES476106A1 (en) 4-Spectinomycylamin and its physiologically acceptable salts, method of preparation and pharmaceutical products containing these substances.
SE8102220L (en) USE OF SUBSTITUTED DERIVATIVES OF 4-PHENYL-4-OXO-2-BUTENIC ACID AS A MEDICINE
ES427079A1 (en) Phenothiazine derivatives, compositions thereof and methods of preparation thereof
ES466851A1 (en) 2-Bromo-6-fluoro-N-(2-imidazolidinylidene)-benzamine and salts thereof and the use to treat hypertension
ES8502116A1 (en) Pyrazolopyridine compounds.
ES450897A1 (en) N-Tetrahydrofurfuryl-noroxymorphones, their salts, and analgesic compositions and methods employing them
ES8203882A1 (en) A heterocyclic compound and its synthesis, pharmaceutical formulations thereof and the use of the compounds and the formulations in medicine.
ES461785A1 (en) Behenic acid esters, compositions thereof and a method of preparation thereof
ES466192A1 (en) Isoquinoline derivatives and pharmaceutical compositions containing them
ES466493A1 (en) 4-phenylbutyric acid dervatives process for their preparation and pharmaceutical compostions containing them
IL71068A0 (en) N-arylpiperazine derivative,its preparation and pharmaceutical compositions containing it
FI862636A (en) PHARMACEUTICAL COMPOSITES WITH NEUROLEPTIC EFFECTS FOR FRUIT FRAMSTAELLNING.
IL58999A0 (en) Pharmaceutical compositions comprising certain imidazolinederivatives
IL61769A0 (en) 2-phenylamino-imidazolines-(2),their preparation and pharmaceutical compositions containing them
ES487971A1 (en) P-Chloroacetophenone oxime compounds and pharmaceutical compositions
FR2363560A1 (en) NEW COMPOUND WITH ANALGESIC ACTION AND THERAPEUTIC COMPOSITIONS IN CONTAINER
ES473909A1 (en) Derivatives of 4-cyclohexyl-1-naphthalene-acetic acid and their use as drugs

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991102