ES474740A1 - A procedure for the preparation of bencil pyrimidines. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of bencil pyrimidines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES474740A1
ES474740A1 ES474740A ES474740A ES474740A1 ES 474740 A1 ES474740 A1 ES 474740A1 ES 474740 A ES474740 A ES 474740A ES 474740 A ES474740 A ES 474740A ES 474740 A1 ES474740 A1 ES 474740A1
Authority
ES
Spain
Prior art keywords
translation
preparation
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES474740A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES474740A1 publication Critical patent/ES474740A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/40—Extraction of image or video features

Abstract

A process for the preparation of bencipyrimidines of the general formula ** (Formula) ** wherein R1 and R2 each represent a C1-6-alkyl group, R3 represents a C1-3 group and R4 represents the group of methylene or a group of C2-4-alkylidene, and of their physiologically compatible acid addition salts. (Machine-translation by Google Translate, not legally binding)
ES474740A 1977-05-05 1978-11-02 A procedure for the preparation of bencil pyrimidines. (Machine-translation by Google Translate, not legally binding) Expired ES474740A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77269A LU77269A1 (en) 1977-05-05 1977-05-05

Publications (1)

Publication Number Publication Date
ES474740A1 true ES474740A1 (en) 1979-04-01

Family

ID=19728559

Family Applications (2)

Application Number Title Priority Date Filing Date
ES474740A Expired ES474740A1 (en) 1977-05-05 1978-11-02 A procedure for the preparation of bencil pyrimidines. (Machine-translation by Google Translate, not legally binding)
ES474739A Expired ES474739A1 (en) 1977-05-05 1978-11-02 A procedure for the preparation of bencil pyrimidines. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES474739A Expired ES474739A1 (en) 1977-05-05 1978-11-02 A procedure for the preparation of bencil pyrimidines. (Machine-translation by Google Translate, not legally binding)

Country Status (6)

Country Link
AU (1) AU517426B2 (en)
BE (1) BE866653A (en)
CH (1) CH642637A5 (en)
ES (2) ES474740A1 (en)
LU (1) LU77269A1 (en)
ZA (1) ZA782459B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07509215A (en) * 1990-11-14 1995-10-12 カイロン　コーポレイション Specific inhibition of dihydrofolate reductase and compounds therefor

Also Published As

Publication number Publication date
ES474739A1 (en) 1979-04-01
BE866653A (en) 1978-11-03
AU3560178A (en) 1979-11-08
CH642637A5 (en) 1984-04-30
LU77269A1 (en) 1979-01-18
ZA782459B (en) 1979-04-25
AU517426B2 (en) 1981-07-30

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