ES470343A1 - Tetranicotinic ester of papaveroline and process for the production thereof - Google Patents

Tetranicotinic ester of papaveroline and process for the production thereof

Info

Publication number
ES470343A1
ES470343A1 ES470343A ES470343A ES470343A1 ES 470343 A1 ES470343 A1 ES 470343A1 ES 470343 A ES470343 A ES 470343A ES 470343 A ES470343 A ES 470343A ES 470343 A1 ES470343 A1 ES 470343A1
Authority
ES
Spain
Prior art keywords
papaveroline
tetranicotinic
ester
production
paperveroline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES470343A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scharper SpA Per L'industria Farmaceutica
SCHARPER SpA
Original Assignee
Scharper SpA Per L'industria Farmaceutica
SCHARPER SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scharper SpA Per L'industria Farmaceutica, SCHARPER SpA filed Critical Scharper SpA Per L'industria Farmaceutica
Publication of ES470343A1 publication Critical patent/ES470343A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Paperveroline derivative for the treatment of arteriopathies, which is easily soluble in water and having the formula: < IMAGE > The invention also concerns the relevant production process, which involves reacting nicotinoyl chloride hydrochloride with papaveroline.
ES470343A 1977-05-30 1978-05-30 Tetranicotinic ester of papaveroline and process for the production thereof Expired ES470343A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT24141/77A IT1143667B (en) 1977-05-30 1977-05-30 PARAVEROLINIC DERIVATIVE WITH A DURABLE ACTION AND PROCEDURE TO OBTAIN IT

Publications (1)

Publication Number Publication Date
ES470343A1 true ES470343A1 (en) 1979-01-01

Family

ID=11212187

Family Applications (1)

Application Number Title Priority Date Filing Date
ES470343A Expired ES470343A1 (en) 1977-05-30 1978-05-30 Tetranicotinic ester of papaveroline and process for the production thereof

Country Status (13)

Country Link
JP (1) JPS53149982A (en)
BE (1) BE867515A (en)
BR (1) BR7803416A (en)
CA (1) CA1084504A (en)
CH (1) CH633446A5 (en)
DE (1) DE2822186A1 (en)
ES (1) ES470343A1 (en)
FR (1) FR2392987A1 (en)
GB (1) GB1593598A (en)
GR (1) GR63731B (en)
IT (1) IT1143667B (en)
MX (1) MX5515E (en)
PT (1) PT68115A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77027C (en) * 1979-07-19 1989-01-10 Andre Buzas SAFETY PREPARATION OF PHARMACOLOGICAL VERKS 1- / 1- (3,4-DIMETOXIFENYL) -3-AMINO-PROPYL / -6,7-DIMETOXY-Isoquinoline INFOERING.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1175246B (en) * 1959-12-14 1964-08-06 Orsymonde Fa Process for the preparation of dimethylpapa-verolin-bis-nicotinic acid ester and its acidic dimaleate
FR794M (en) * 1960-12-02 1961-09-11

Also Published As

Publication number Publication date
CH633446A5 (en) 1982-12-15
FR2392987B1 (en) 1982-04-23
GB1593598A (en) 1981-07-22
CA1084504A (en) 1980-08-26
MX5515E (en) 1983-09-14
GR63731B (en) 1979-12-04
BR7803416A (en) 1979-01-02
JPS53149982A (en) 1978-12-27
PT68115A (en) 1978-06-01
BE867515A (en) 1978-09-18
FR2392987A1 (en) 1978-12-29
JPS572715B2 (en) 1982-01-18
DE2822186A1 (en) 1978-12-14
IT1143667B (en) 1986-10-22

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