ES469631A1 - Pyrole derivative process for preparing same and composition containing same - Google Patents

Pyrole derivative process for preparing same and composition containing same

Info

Publication number
ES469631A1
ES469631A1 ES469631A ES469631A ES469631A1 ES 469631 A1 ES469631 A1 ES 469631A1 ES 469631 A ES469631 A ES 469631A ES 469631 A ES469631 A ES 469631A ES 469631 A1 ES469631 A1 ES 469631A1
Authority
ES
Spain
Prior art keywords
same
pyrole
composition containing
derivative process
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES469631A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB19465/77A external-priority patent/GB1601107A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES469631A1 publication Critical patent/ES469631A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Compounds of the formula < IMAGE > and derivatives thereof, in which R1 is hydrogen or methyl, Ar is a phenyl, a substituted phenyl or a thienyl, where the substituted phenyl is substituted by one or two groups selected from fluorine, chlorine, bromine, methyl, methoxy or trifluoromethyl, and X is a CO or CHOH group. The said pyrrole derivatives have an anti-inflammatory activity.
ES469631A 1977-05-10 1978-05-09 Pyrole derivative process for preparing same and composition containing same Expired ES469631A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB19465/77A GB1601107A (en) 1977-05-10 1977-05-10 Pyrrole derivatives
GB352978 1978-01-28
GB575178 1978-02-14

Publications (1)

Publication Number Publication Date
ES469631A1 true ES469631A1 (en) 1980-03-01

Family

ID=27254285

Family Applications (1)

Application Number Title Priority Date Filing Date
ES469631A Expired ES469631A1 (en) 1977-05-10 1978-05-09 Pyrole derivative process for preparing same and composition containing same

Country Status (12)

Country Link
JP (1) JPS53141268A (en)
AU (1) AU526256B2 (en)
CA (1) CA1100142A (en)
CH (1) CH640225A5 (en)
DE (1) DE2819463A1 (en)
DK (1) DK204078A (en)
ES (1) ES469631A1 (en)
FR (1) FR2390431A1 (en)
IE (1) IE46825B1 (en)
IL (1) IL54642A (en)
NL (1) NL7804942A (en)
SE (1) SE7805282L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0032314A1 (en) * 1980-01-09 1981-07-22 Beecham Group Plc Aroylpyrrole derivatives, processes for their preparation and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles

Also Published As

Publication number Publication date
CH640225A5 (en) 1983-12-30
SE7805282L (en) 1978-11-11
DE2819463A1 (en) 1978-11-16
CA1100142A (en) 1981-04-28
AU3599078A (en) 1979-11-15
FR2390431B1 (en) 1981-11-06
IE780942L (en) 1978-11-10
IE46825B1 (en) 1983-10-05
DK204078A (en) 1978-11-11
FR2390431A1 (en) 1978-12-08
IL54642A0 (en) 1978-07-31
AU526256B2 (en) 1982-12-23
IL54642A (en) 1982-03-31
JPS53141268A (en) 1978-12-08
NL7804942A (en) 1978-11-14

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