ES465096A1 - Process for brominating ergocryptine - Google Patents

Process for brominating ergocryptine

Info

Publication number
ES465096A1
ES465096A1 ES465096A ES465096A ES465096A1 ES 465096 A1 ES465096 A1 ES 465096A1 ES 465096 A ES465096 A ES 465096A ES 465096 A ES465096 A ES 465096A ES 465096 A1 ES465096 A1 ES 465096A1
Authority
ES
Spain
Prior art keywords
ergocryptine
brominating
alpha
bromosaccharin
bromination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES465096A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lek Pharmaceuticals dd
Original Assignee
Lek Pharmaceuticals and Chemical Co dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals and Chemical Co dd filed Critical Lek Pharmaceuticals and Chemical Co dd
Publication of ES465096A1 publication Critical patent/ES465096A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Procedure for the preparation of 2-bromo-alpha-ergocryptine characterized by performing the bromination of alpha-ergocryptine in an inert atmosphere with pyrrolidone hydrotribromide or N-bromosaccharin in the solution of a cyclic ether in the presence of a radical initiator at room temperature or slightly elevated. (Machine-translation by Google Translate, not legally binding)
ES465096A 1976-12-23 1977-12-15 Process for brominating ergocryptine Expired ES465096A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU3134/76A YU39786B (en) 1976-12-23 1976-12-23 Process for preparing 2-bromo-alfa-ergocriptine

Publications (1)

Publication Number Publication Date
ES465096A1 true ES465096A1 (en) 1978-09-01

Family

ID=25559398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES465096A Expired ES465096A1 (en) 1976-12-23 1977-12-15 Process for brominating ergocryptine

Country Status (18)

Country Link
JP (1) JPS5384997A (en)
BE (1) BE903269Q (en)
CS (1) CS215105B2 (en)
DD (1) DD134101A1 (en)
DE (1) DE2752532C3 (en)
ES (1) ES465096A1 (en)
FR (1) FR2375242A1 (en)
GB (1) GB1574479A (en)
HK (1) HK4786A (en)
HU (1) HU176817B (en)
KE (1) KE3572A (en)
PL (1) PL106363B1 (en)
PT (1) PT67340A (en)
RO (1) RO71277A (en)
SG (1) SG71885G (en)
SU (1) SU795477A3 (en)
UA (1) UA8031A1 (en)
YU (1) YU39786B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU216177A (en) 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine
YU39849B (en) * 1978-09-26 1985-04-30 Lek Tovarna Farmacevtskih Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507249A (en) * 1968-05-31 1971-05-15 Sandoz Ag Process for the preparation of 2-bromo-a-ergocryptine
YU216177A (en) * 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine

Also Published As

Publication number Publication date
YU313476A (en) 1982-05-31
PL106363B1 (en) 1979-12-31
SG71885G (en) 1988-09-30
HK4786A (en) 1986-01-31
PT67340A (en) 1977-12-01
JPS5550038B2 (en) 1980-12-16
PL202697A1 (en) 1978-07-31
FR2375242A1 (en) 1978-07-21
RO71277A (en) 1982-02-01
YU39786B (en) 1985-04-30
DE2752532C3 (en) 1980-09-18
BE903269Q (en) 1986-01-16
UA8031A1 (en) 1995-12-26
CS215105B2 (en) 1982-07-30
KE3572A (en) 1985-11-08
JPS5384997A (en) 1978-07-26
SU795477A3 (en) 1981-01-07
FR2375242B1 (en) 1983-01-14
DE2752532B2 (en) 1979-12-06
HU176817B (en) 1981-05-28
GB1574479A (en) 1980-09-10
DD134101A1 (en) 1979-02-07
DE2752532A1 (en) 1978-06-29

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Legal Events

Date Code Title Description
PC1A Transfer granted