ES461325A1 - D-homosteroids - Google Patents
D-homosteroidsInfo
- Publication number
- ES461325A1 ES461325A1 ES461325A ES461325A ES461325A1 ES 461325 A1 ES461325 A1 ES 461325A1 ES 461325 A ES461325 A ES 461325A ES 461325 A ES461325 A ES 461325A ES 461325 A1 ES461325 A1 ES 461325A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- acyl
- beta
- alpha
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A process for the preparation of D-homosteroids of the general formula ** (Formula) ** where the dashed lines in ring A designate optional carbon-carbon bonds, R3 represents an oxo group or, when ring A is unsaturated, an Oxo group, (alpha-H, beta-OH) or (alpha-H, beta-O-acyl); R17aBeta represents a hydrogen atom or a C1-C10 alkyl group; benzyl, cyclohexylmethyl, acyl, tetrahydropyranyl, or cycloalkenyl and R17aAlpha represents a hydrogen atom or a lower alkyl, ethynyl, vinyl, or propadienyl group. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1456475A CH616436A5 (en) | 1975-11-11 | 1975-11-11 | Process for the preparation of D-homosteroids. |
| CH1160476 | 1976-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES461325A1 true ES461325A1 (en) | 1978-12-16 |
Family
ID=25708627
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES461325A Expired ES461325A1 (en) | 1975-11-11 | 1977-08-03 | D-homosteroids |
| ES461326A Expired ES461326A1 (en) | 1975-11-11 | 1977-08-03 | D-homosteroids |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES461326A Expired ES461326A1 (en) | 1975-11-11 | 1977-08-03 | D-homosteroids |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS5259148A (en) |
| AT (1) | AT354653B (en) |
| AU (1) | AU505624B2 (en) |
| CA (1) | CA1082686A (en) |
| DD (1) | DD128852A5 (en) |
| DE (1) | DE2651364A1 (en) |
| ES (2) | ES461325A1 (en) |
| FR (1) | FR2331329A1 (en) |
| GB (1) | GB1564144A (en) |
| GR (1) | GR70298B (en) |
| IE (1) | IE43985B1 (en) |
| IL (1) | IL50854A (en) |
| LU (1) | LU76161A1 (en) |
| MC (1) | MC1121A1 (en) |
| NL (1) | NL7612538A (en) |
| NZ (1) | NZ182539A (en) |
| PH (1) | PH13603A (en) |
| PL (1) | PL193604A1 (en) |
| PT (1) | PT65821B (en) |
| SU (1) | SU679147A3 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788218A (en) * | 1984-05-21 | 1988-11-29 | Sri International | 17 a β-hydroxy-7 α-methyl-d-homo-19-norandrost-4,16-diene-3-one and the 17-esters thereof: methods of preparation and uses |
| GB2362648A (en) * | 2000-05-23 | 2001-11-28 | Univerzita Palackeho V Olomouc | Triterpenoid derivatives |
| CA2534831A1 (en) * | 2003-08-21 | 2005-03-10 | Schering Ag | .delta.15-d-homosteroids having an androgenic effect |
-
1976
- 1976-11-05 NZ NZ182539A patent/NZ182539A/en unknown
- 1976-11-05 IL IL50854A patent/IL50854A/en unknown
- 1976-11-06 MC MC761217A patent/MC1121A1/en unknown
- 1976-11-08 IE IE2476/76A patent/IE43985B1/en unknown
- 1976-11-09 JP JP51133847A patent/JPS5259148A/en active Pending
- 1976-11-09 AU AU19431/76A patent/AU505624B2/en not_active Expired
- 1976-11-09 DD DD7600195685A patent/DD128852A5/en unknown
- 1976-11-09 PH PH19111A patent/PH13603A/en unknown
- 1976-11-10 GB GB46765/76A patent/GB1564144A/en not_active Expired
- 1976-11-10 SU SU762418751A patent/SU679147A3/en active
- 1976-11-10 DE DE19762651364 patent/DE2651364A1/en not_active Withdrawn
- 1976-11-10 PL PL19360476A patent/PL193604A1/en unknown
- 1976-11-10 FR FR7633899A patent/FR2331329A1/en active Granted
- 1976-11-10 AT AT834476A patent/AT354653B/en not_active IP Right Cessation
- 1976-11-10 GR GR52152A patent/GR70298B/el unknown
- 1976-11-10 LU LU76161A patent/LU76161A1/xx unknown
- 1976-11-10 PT PT65821A patent/PT65821B/en unknown
- 1976-11-10 CA CA265,305A patent/CA1082686A/en not_active Expired
- 1976-11-11 NL NL7612538A patent/NL7612538A/en not_active Application Discontinuation
-
1977
- 1977-08-03 ES ES461325A patent/ES461325A1/en not_active Expired
- 1977-08-03 ES ES461326A patent/ES461326A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SU679147A3 (en) | 1979-08-05 |
| DD128852A5 (en) | 1977-12-14 |
| CA1082686A (en) | 1980-07-29 |
| PT65821B (en) | 1978-10-10 |
| IL50854A (en) | 1979-12-30 |
| ES461326A1 (en) | 1978-12-01 |
| PL193604A1 (en) | 1979-03-26 |
| PH13603A (en) | 1980-08-05 |
| GR70298B (en) | 1982-09-06 |
| MC1121A1 (en) | 1977-08-12 |
| PT65821A (en) | 1976-12-01 |
| AT354653B (en) | 1979-01-25 |
| IE43985L (en) | 1977-05-11 |
| FR2331329B1 (en) | 1981-11-27 |
| AU1943176A (en) | 1978-05-18 |
| JPS5259148A (en) | 1977-05-16 |
| IL50854A0 (en) | 1977-01-31 |
| NL7612538A (en) | 1977-05-13 |
| DE2651364A1 (en) | 1977-05-12 |
| GB1564144A (en) | 1980-04-02 |
| ATA834476A (en) | 1979-06-15 |
| NZ182539A (en) | 1979-07-11 |
| LU76161A1 (en) | 1977-12-13 |
| AU505624B2 (en) | 1979-11-29 |
| FR2331329A1 (en) | 1977-06-10 |
| IE43985B1 (en) | 1981-07-15 |
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