ES352066A1 - A procedure for the preparation of 17-alpha-propodien steroids. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of 17-alpha-propodien steroids. (Machine-translation by Google Translate, not legally binding)
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Roche Palo Alto LLC
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Roche Palo Alto LLC
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A procedure for the preparation of 17α-propadien-steroids of the formula: **(See formula)** where A represents: **(See formula)** where R is hydrogen or methyl; R1 is hydrogen, lower alkyl, tetrahydropyran-2-yl, tetrahydrofuran-2-yl, cyclopentyl, cyclohexyl or a hydrocarbon carboxylic acyl group; R2 is hydrogen, methyl, ethyl, or n-propyl; R3 is hydrogen, tetrahydropyran-2-yl, tetrahydrofuran-2-yl or a hydrocarbon carboxylic acyl group; R4 is hydrogen, methyl or chlorine; and R5 is an oxygen atom or the group (see formula) where R6 is hydrogen, tetrahydropyran-2-yl, tetrahydrofuran-2-yl or a hydrocarbon carboxylic acyl group. which consists of treating a 17α-dihalocielopropil-steroid of the androstane, 19-nor-androstane or estratriene series with magnesium, potassium tert-butoxide, sodium butyllithium or methylsulfinylcarbanion, in an inert organic solvent against the reaction. (Machine-translation by Google Translate, not legally binding)
ES352066A1968-03-271968-03-27A procedure for the preparation of 17-alpha-propodien steroids. (Machine-translation by Google Translate, not legally binding)
ExpiredES352066A1
(en)