ES411302A1 - Procedure for the preparation of 2-oxo-1 pirrolidinoacetamide. (Machine-translation by Google Translate, not legally binding)
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Procedure for the preparation of 2-oxo-1 pirrolidinoacetamide. (Machine-translation by Google Translate, not legally binding)
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INST INTERNACIONAL TERAPEUTICO
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INST INTERNACIONAL TERAPEUTICO
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Publication of ES411302A1publicationCriticalpatent/ES411302A1/en
Procedure for the preparation of 2-oxo-1-pyrrolidinoacetainide, of the formula ** (see formula) ** Characterized in that, in a first step, an alkaline metal salt of 2-oxo-pyrrolidine is reacted with chloroacetonitrile forming 2-oxo-l-pyrrolidinoacetonitrile, which, in a second step, is hydrolyzed to its corresponding 2- oxo-1-pyrrolidinoacetamide by the action of inorganic and organic acids, either under the action of inorganic or organic bases, or by the action of hydrogen peroxide, or the combination thereof with bases; whose process is optionally conducted, in the presence or absence of solvents and at temperatures varying between 0ºC and the boiling point of the reaction mass. (Machine-translation by Google Translate, not legally binding)
ES411302A1973-02-051973-02-05Procedure for the preparation of 2-oxo-1 pirrolidinoacetamide. (Machine-translation by Google Translate, not legally binding)
ExpiredES411302A1
(en)
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