ES461300A1 - myxomatosis vaccine prodn. from attenuated virus strain - by passaging on rabbit kidney and chicken embryo cells - Google Patents

myxomatosis vaccine prodn. from attenuated virus strain - by passaging on rabbit kidney and chicken embryo cells

Info

Publication number
ES461300A1
ES461300A1 ES461300A ES461300A ES461300A1 ES 461300 A1 ES461300 A1 ES 461300A1 ES 461300 A ES461300 A ES 461300A ES 461300 A ES461300 A ES 461300A ES 461300 A1 ES461300 A1 ES 461300A1
Authority
ES
Spain
Prior art keywords
passaging
myxomatosis
vaccine
chicken embryo
virus strain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES461300A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Publication of ES461300A1 publication Critical patent/ES461300A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/275—Poxviridae, e.g. avipoxvirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24211—Parapoxvirus, e.g. Orf virus
    • C12N2710/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Method for preparing a myxomatosis vaccine comprises first preparing a strain of reduced pathogenicity of the 1025 virus type (Pasteur Institute, deposited 21st July, 1976). This is achieved by successive passaging of a spontaneous virus strain on rabbit kidney cells, cloning the resulting population, then passaging on chicken embryo cells. A cell culture is then prepd. from the new virus strain so obtd. Pref. both passaging phases are carried out at 30-35, esp. 33 degrees C and the number of passages on kidney cells is 60-100, and the number of chicken embryo cells 3-30. Used to protect rabbits and hares against myxomatosis. The vaccine is more effective than that prepd. from the Shope fibroma virus.
ES461300A 1976-08-05 1977-08-02 myxomatosis vaccine prodn. from attenuated virus strain - by passaging on rabbit kidney and chicken embryo cells Expired ES461300A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7624243A FR2384845A1 (en) 1976-08-05 1976-08-05 myxomatosis vaccine prodn. from attenuated virus strain - by passaging on rabbit kidney and chicken embryo cells

Publications (1)

Publication Number Publication Date
ES461300A1 true ES461300A1 (en) 1978-09-01

Family

ID=9176679

Family Applications (1)

Application Number Title Priority Date Filing Date
ES461300A Expired ES461300A1 (en) 1976-08-05 1977-08-02 myxomatosis vaccine prodn. from attenuated virus strain - by passaging on rabbit kidney and chicken embryo cells

Country Status (3)

Country Link
DE (1) DE2734660C3 (en)
ES (1) ES461300A1 (en)
FR (1) FR2384845A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3021960C2 (en) * 1980-06-12 1984-01-12 Felten & Guilleaume Fernmeldeanlagen GmbH, 8500 Nürnberg Circuit arrangement in the form of a quadrupole to simulate an inductance
UA82466C2 (en) * 2001-07-18 2008-04-25 Бавариан Нордика А/С Method for intensification of chordopoxvirus amplification

Also Published As

Publication number Publication date
DE2734660B2 (en) 1980-12-04
DE2734660A1 (en) 1978-02-09
FR2384845A1 (en) 1978-10-20
DE2734660C3 (en) 1982-02-04
FR2384845B1 (en) 1980-06-06

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103