ES459322A1 - Un procedimiento para preparar piridin-6-epoxietanos susti- tuidos. - Google Patents

Un procedimiento para preparar piridin-6-epoxietanos susti- tuidos.

Info

Publication number
ES459322A1
ES459322A1 ES459322A ES459322A ES459322A1 ES 459322 A1 ES459322 A1 ES 459322A1 ES 459322 A ES459322 A ES 459322A ES 459322 A ES459322 A ES 459322A ES 459322 A1 ES459322 A1 ES 459322A1
Authority
ES
Spain
Prior art keywords
manufacture
pyrimidine derivative
formula
epoxyethanes
tetrahydrofuran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES459322A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES459322A1 publication Critical patent/ES459322A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procedimiento para preparar piridin-6-epoxietanos sustituidos de la fórmula: (ver imagen 1) caracterizado porque se hace reaccionar un compuesto de la fórmula: (ver imagen 2) Con yoduro o clorudo de trimetilsulfonio en presencia de hidruro de sodio y dimetilsulfóxido y/o tetrahidrofurano, y se trata la mezcla resultante con agua.
ES459322A 1973-12-26 1977-05-31 Un procedimiento para preparar piridin-6-epoxietanos susti- tuidos. Expired ES459322A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42845173A 1973-12-26 1973-12-26

Publications (1)

Publication Number Publication Date
ES459322A1 true ES459322A1 (es) 1978-03-16

Family

ID=23698949

Family Applications (1)

Application Number Title Priority Date Filing Date
ES459322A Expired ES459322A1 (es) 1973-12-26 1977-05-31 Un procedimiento para preparar piridin-6-epoxietanos susti- tuidos.

Country Status (6)

Country Link
JP (1) JPS6056716B2 (es)
AT (1) AT342589B (es)
BE (1) BE823616A (es)
ES (1) ES459322A1 (es)
PL (1) PL110958B1 (es)
SU (1) SU604486A3 (es)

Also Published As

Publication number Publication date
JPS6056716B2 (ja) 1985-12-11
JPS60185779A (ja) 1985-09-21
BE823616A (fr) 1975-06-20
ATA1009874A (de) 1977-08-15
AT342589B (de) 1978-04-10
SU604486A3 (ru) 1978-04-25
PL110958B1 (en) 1980-08-30

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