ES458164A1 - 1,4-disubstituted 4-imidazolin-2-ones,1,4-disubstituted imidazolin-2-ones and 1,4-disubstituted imidazolidin-2-thiones and their use in non-asymmetric synthesis of tetramisole levamisole and their derivatives - Google Patents
1,4-disubstituted 4-imidazolin-2-ones,1,4-disubstituted imidazolin-2-ones and 1,4-disubstituted imidazolidin-2-thiones and their use in non-asymmetric synthesis of tetramisole levamisole and their derivativesInfo
- Publication number
- ES458164A1 ES458164A1 ES458164A ES458164A ES458164A1 ES 458164 A1 ES458164 A1 ES 458164A1 ES 458164 A ES458164 A ES 458164A ES 458164 A ES458164 A ES 458164A ES 458164 A1 ES458164 A1 ES 458164A1
- Authority
- ES
- Spain
- Prior art keywords
- disubstituted
- ones
- imidazolin
- derivatives
- tetramisole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for preparing substituted imidazolidine derivatives of formula HY wherein R2 is phenyl or phenyl substituted with up to two groups consisting of C1-C6 alkyl, halo or trifluoromethyl; and Y is a pharmaceutically acceptable anion, characterized by heating a substituted imidazolidinethione of the formula: *** See image 01 *** See image 02 (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68031176A | 1976-04-26 | 1976-04-26 | |
US05/739,924 US4090025A (en) | 1976-04-26 | 1976-11-08 | Intermediates for synthesis of tetramisole, levamisole and their derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ES458164A1 true ES458164A1 (en) | 1978-08-16 |
Family
ID=27102431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES458164A Expired ES458164A1 (en) | 1976-04-26 | 1977-04-26 | 1,4-disubstituted 4-imidazolin-2-ones,1,4-disubstituted imidazolin-2-ones and 1,4-disubstituted imidazolidin-2-thiones and their use in non-asymmetric synthesis of tetramisole levamisole and their derivatives |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS52142067A (en) |
AU (1) | AU2341277A (en) |
DD (1) | DD131175A5 (en) |
DE (1) | DE2718059A1 (en) |
DK (1) | DK181177A (en) |
ES (1) | ES458164A1 (en) |
FR (1) | FR2370735A1 (en) |
GB (2) | GB1579861A (en) |
IL (1) | IL51654A0 (en) |
IT (1) | IT1086883B (en) |
NL (1) | NL7704424A (en) |
NO (1) | NO771422L (en) |
NZ (1) | NZ183622A (en) |
SE (1) | SE7704745L (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL51639A0 (en) * | 1976-04-26 | 1977-05-31 | American Cyanamid Co | New synthesis of tetramisole levamisole and their derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3726894A (en) * | 1971-06-24 | 1973-04-10 | American Cyanamid Co | The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione |
GB1435900A (en) * | 1972-10-04 | 1976-05-19 | Agfa Gevaert | Method for the preparation of planographic printing plates |
FR2258379A1 (en) * | 1974-01-21 | 1975-08-18 | Aries Robert | Imidazo thiazolidine anthelmintics - prepd from an ethylene thiourea and a haloethanol, halogenation and cyclisation |
-
1977
- 1977-03-14 IL IL51654A patent/IL51654A0/en unknown
- 1977-03-16 NZ NZ183622A patent/NZ183622A/en unknown
- 1977-03-17 GB GB11485/77A patent/GB1579861A/en not_active Expired
- 1977-03-17 GB GB3668/79A patent/GB1579862A/en not_active Expired
- 1977-03-18 AU AU23412/77A patent/AU2341277A/en not_active Expired
- 1977-04-07 IT IT48871/77A patent/IT1086883B/en active
- 1977-04-22 NL NL7704424A patent/NL7704424A/en not_active Application Discontinuation
- 1977-04-22 DE DE19772718059 patent/DE2718059A1/en not_active Withdrawn
- 1977-04-25 SE SE7704745A patent/SE7704745L/en unknown
- 1977-04-25 NO NO771422A patent/NO771422L/en unknown
- 1977-04-25 DK DK181177A patent/DK181177A/en not_active Application Discontinuation
- 1977-04-26 DD DD7700198605A patent/DD131175A5/en unknown
- 1977-04-26 ES ES458164A patent/ES458164A1/en not_active Expired
- 1977-04-26 JP JP4745477A patent/JPS52142067A/en active Pending
- 1977-04-26 FR FR7712567A patent/FR2370735A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
NZ183622A (en) | 1980-04-28 |
NO771422L (en) | 1977-10-27 |
NL7704424A (en) | 1977-10-28 |
JPS52142067A (en) | 1977-11-26 |
DK181177A (en) | 1977-10-27 |
DE2718059A1 (en) | 1977-11-10 |
AU2341277A (en) | 1978-09-21 |
DD131175A5 (en) | 1978-06-07 |
IT1086883B (en) | 1985-05-31 |
FR2370735A1 (en) | 1978-06-09 |
IL51654A0 (en) | 1977-05-31 |
GB1579862A (en) | 1980-11-26 |
GB1579861A (en) | 1980-11-26 |
SE7704745L (en) | 1977-10-27 |
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