ES456941A1 - Novel isobutylamide compound and process for preparing same - Google Patents

Novel isobutylamide compound and process for preparing same

Info

Publication number
ES456941A1
ES456941A1 ES456941A ES456941A ES456941A1 ES 456941 A1 ES456941 A1 ES 456941A1 ES 456941 A ES456941 A ES 456941A ES 456941 A ES456941 A ES 456941A ES 456941 A1 ES456941 A1 ES 456941A1
Authority
ES
Spain
Prior art keywords
novel
preparing same
isobutylamide compound
chlrophenoxy
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES456941A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Publication of ES456941A1 publication Critical patent/ES456941A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

New N-cyanoalkyl-alpha-halophenoxy-isobutyramides are of formula (I): (where R1 is halo gen, n = 2-6). Cpds. (I) have hypolipaemic activity, e.g. (I, r1 = Cl, n = 2) is more effective in reducing blood cholesterol levels than nicotinic acid and more effective in reducing triglyceride levels than ethyl 2-(4-chlrophenoxy)-2-methylpropionate. In an example, (I, R1 = Cl, n = 2) is prepd. from 3-aminopropionitrile and alpha-(p-chlrophenoxy)isobutyryl chloride.
ES456941A 1976-03-17 1977-03-17 Novel isobutylamide compound and process for preparing same Expired ES456941A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1063576 1976-03-17

Publications (1)

Publication Number Publication Date
ES456941A1 true ES456941A1 (en) 1978-12-16

Family

ID=9971513

Family Applications (1)

Application Number Title Priority Date Filing Date
ES456941A Expired ES456941A1 (en) 1976-03-17 1977-03-17 Novel isobutylamide compound and process for preparing same

Country Status (16)

Country Link
JP (1) JPS52113931A (en)
AR (1) AR211888A1 (en)
AT (1) AT346316B (en)
BE (1) BE852558A (en)
CH (1) CH598202A5 (en)
DE (1) DE2711738B2 (en)
DK (1) DK118077A (en)
ES (1) ES456941A1 (en)
FR (2) FR2344527A1 (en)
IN (1) IN145100B (en)
MX (1) MX4397E (en)
NL (1) NL166011C (en)
NZ (1) NZ183561A (en)
OA (1) OA05599A (en)
PT (1) PT66306B (en)
ZA (1) ZA771614B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2043625T3 (en) * 1986-08-29 1994-01-01 Shell Int Research ARILOXICARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932168A (en) * 1971-11-17 1976-01-13 Abbott Laboratories Substituted aryloxyacetamido nitrile derivatives as carbohydrate deposition agents

Also Published As

Publication number Publication date
AR211888A1 (en) 1978-03-31
BE852558A (en) 1977-07-18
FR2344529A1 (en) 1977-10-14
DE2711738B2 (en) 1979-04-12
NL166011C (en) 1981-06-15
AT346316B (en) 1978-11-10
JPS52113931A (en) 1977-09-24
NL166011B (en) 1981-01-15
JPS5647178B2 (en) 1981-11-07
FR2344529B1 (en) 1980-05-16
OA05599A (en) 1981-04-30
FR2344527B1 (en) 1980-03-14
NZ183561A (en) 1978-06-20
NL7702893A (en) 1977-09-20
ZA771614B (en) 1978-02-22
CH598202A5 (en) 1978-04-28
PT66306B (en) 1978-08-11
DE2711738C3 (en) 1979-12-06
PT66306A (en) 1977-04-01
FR2344527A1 (en) 1977-10-14
DK118077A (en) 1977-09-18
ATA183177A (en) 1978-03-15
DE2711738A1 (en) 1977-09-22
MX4397E (en) 1982-04-23
IN145100B (en) 1978-08-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103