ES455473A1 - Process for the preparation of factor 8 concentrates - Google Patents

Process for the preparation of factor 8 concentrates

Info

Publication number
ES455473A1
ES455473A1 ES455473A ES455473A ES455473A1 ES 455473 A1 ES455473 A1 ES 455473A1 ES 455473 A ES455473 A ES 455473A ES 455473 A ES455473 A ES 455473A ES 455473 A1 ES455473 A1 ES 455473A1
Authority
ES
Spain
Prior art keywords
factor
preparation
concentrates
factor viii
polyol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES455473A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RECHERCHES HEMATOLOGIQUES
Original Assignee
RECHERCHES HEMATOLOGIQUES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/653,973 external-priority patent/US4069216A/en
Application filed by RECHERCHES HEMATOLOGIQUES filed Critical RECHERCHES HEMATOLOGIQUES
Publication of ES455473A1 publication Critical patent/ES455473A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

Preparation process of an antihemophilic factor concentrate, called factor viii, characterized in that it comprises the step consisting of maintaining a buffer solution containing factor viii and approximately 6% of polyol at a temperature of about 0º to 5º until precipitation occurs . (Machine-translation by Google Translate, not legally binding)
ES455473A 1976-01-30 1977-01-29 Process for the preparation of factor 8 concentrates Expired ES455473A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/653,973 US4069216A (en) 1975-06-16 1976-01-30 Simplified methods for preparation of very high purity Factor VIII concentrate

Publications (1)

Publication Number Publication Date
ES455473A1 true ES455473A1 (en) 1978-01-01

Family

ID=24623016

Family Applications (1)

Application Number Title Priority Date Filing Date
ES455473A Expired ES455473A1 (en) 1976-01-30 1977-01-29 Process for the preparation of factor 8 concentrates

Country Status (16)

Country Link
JP (1) JPS52102410A (en)
AR (1) AR214625A1 (en)
AT (1) AT354632B (en)
BE (1) BE850852A (en)
BR (1) BR7700554A (en)
CA (1) CA1101332A (en)
DE (1) DE2703620C2 (en)
DK (1) DK146855C (en)
ES (1) ES455473A1 (en)
FR (1) FR2339621A1 (en)
GB (1) GB1557609A (en)
LU (1) LU76652A1 (en)
MX (1) MX5197E (en)
NL (1) NL179290C (en)
NO (1) NO145563C (en)
SE (1) SE442953B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE448945B (en) * 1979-12-20 1987-03-30 Blombaeck E G B PROCEDURE FOR CLEANING AND / OR CONCENTRATION OF THE FACTOR VIII COMPLEX
AT369263B (en) * 1980-08-27 1982-12-27 Immuno Ag METHOD FOR PRODUCING A FACTOR VIII (AHF) HIGH CONCENTRATE
EP0062456B1 (en) * 1981-04-08 1988-12-21 United Kingdom Atomic Energy Authority Blood fractionation improvement
US4382028A (en) * 1982-07-19 1983-05-03 Monsanto Company Separation of plasma proteins from cell culture systems
FR2535173A1 (en) * 1982-11-03 1984-05-04 Protein Sa Products obtained from the blood of abattoir animals and method for obtaining them.
FR2603805A1 (en) * 1986-09-16 1988-03-18 Transfusion Sanguine Assoc Rgl PROCESS FOR THE INACTIVATION BY OZONOLYSIS OF CONTAMINANT MICROORGANISMS PRESENT IN ESSENTIALLY PROTECTED BIOLOGICAL MATERIALS, THE PRODUCTS OBTAINED AND THEIR BIOLOGICAL AND ANALYTICAL APPLICATIONS
HRP940645A2 (en) * 1993-10-06 1996-12-31 Immuno Ag Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained
PL2864026T3 (en) 2012-06-26 2018-11-30 Swm Luxembourg S A R L Membrane filtration using low energy feed spacer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL286954A (en) * 1962-01-03
US3652530A (en) * 1967-08-28 1972-03-28 American Nat Red Cross Antihemophilic factor prepared from blood plasma using polyethylene glycol
US3631018A (en) * 1970-05-01 1971-12-28 Baxter Laboratories Inc Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate
US3682881A (en) * 1970-10-02 1972-08-08 Baxter Laboratories Inc Fractionation of plasma using glycine and polyethylene glycol
US3770631A (en) * 1971-06-29 1973-11-06 Baxter Laboratories Inc Clarification of blood serum and plasma
US3839314A (en) * 1971-06-29 1974-10-01 Baxter Laboratories Inc Clarification of blood serum and plasma using block copolymers of ethylene oxide and polyoxypropylene
US4073886A (en) * 1973-01-30 1978-02-14 Baxter Travenol Laboratories, Inc. Blood fractionation process using block copolymers of ethylene oxide and polyoxypropylene
US3893990A (en) * 1973-04-05 1975-07-08 Baxter Laboratories Inc Clarification of blood serum and plasma using a block copolymer of ethylene oxide and polyoxypropylene

Also Published As

Publication number Publication date
JPS6242887B2 (en) 1987-09-10
NO145563C (en) 1982-04-21
ATA53277A (en) 1979-06-15
BR7700554A (en) 1977-10-04
FR2339621A1 (en) 1977-08-26
DK146855C (en) 1984-07-02
MX5197E (en) 1983-04-25
NL7700927A (en) 1977-08-02
AT354632B (en) 1979-01-25
CA1101332A (en) 1981-05-19
AR214625A1 (en) 1979-07-13
DK146855B (en) 1984-01-23
DE2703620C2 (en) 1984-11-22
NO145563B (en) 1982-01-11
JPS52102410A (en) 1977-08-27
NO770293L (en) 1977-08-02
NL179290B (en) 1986-03-17
DK36477A (en) 1977-07-31
GB1557609A (en) 1979-12-12
SE7700864L (en) 1977-07-31
LU76652A1 (en) 1978-09-13
NL179290C (en) 1986-08-18
FR2339621B1 (en) 1980-06-06
BE850852A (en) 1977-07-28
SE442953B (en) 1986-02-10
DE2703620A1 (en) 1977-08-04

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