ES454453A1 - Metodo para preparar una composicion que contiene factor an-tihermofilico adaptada para ser rapidamente solubilizada. - Google Patents

Metodo para preparar una composicion que contiene factor an-tihermofilico adaptada para ser rapidamente solubilizada.

Info

Publication number
ES454453A1
ES454453A1 ES454453A ES454453A ES454453A1 ES 454453 A1 ES454453 A1 ES 454453A1 ES 454453 A ES454453 A ES 454453A ES 454453 A ES454453 A ES 454453A ES 454453 A1 ES454453 A1 ES 454453A1
Authority
ES
Spain
Prior art keywords
composition
preparing same
rapidly solubilized
ahf
solubilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES454453A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter Travenol Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/729,758 external-priority patent/US4089944A/en
Application filed by Baxter Travenol Laboratories Inc filed Critical Baxter Travenol Laboratories Inc
Publication of ES454453A1 publication Critical patent/ES454453A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Método para preparar una composición que contiene factor antihemofílico adaptada para ser rápidamente solubilizada por reconstitución con un líquido reconstituyente, para producir una solución que contiene una cantidad terapéuticamente eficaz de factor antihemofílico (FAH), caracterizado por añadir a dicha composición un carbohidrato soluble en agua, en cantidad suficiente para solubilizar la composición en el líquido reconstituyente dentro de aproximadamente 90 segundos.
ES454453A 1975-12-22 1976-12-21 Metodo para preparar una composicion que contiene factor an-tihermofilico adaptada para ser rapidamente solubilizada. Expired ES454453A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64317875A 1975-12-22 1975-12-22
US05/729,758 US4089944A (en) 1975-12-22 1976-10-05 Rapidly solubilized AHF composition and process for preparing same

Publications (1)

Publication Number Publication Date
ES454453A1 true ES454453A1 (es) 1978-04-01

Family

ID=27094202

Family Applications (1)

Application Number Title Priority Date Filing Date
ES454453A Expired ES454453A1 (es) 1975-12-22 1976-12-21 Metodo para preparar una composicion que contiene factor an-tihermofilico adaptada para ser rapidamente solubilizada.

Country Status (7)

Country Link
JP (1) JPS5282716A (es)
AT (1) AT351158B (es)
CA (1) CA1066189A (es)
DE (1) DE2653534C2 (es)
ES (1) ES454453A1 (es)
GB (1) GB1540610A (es)
MX (1) MX4730E (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186192A (en) * 1978-12-18 1980-01-29 Cutter Laboratories, Inc. Stabilized immune serum globulin
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
DE3432083A1 (de) * 1984-08-31 1986-03-06 Behringwerke Ag, 3550 Marburg Pasteurisierte, isoagglutininfreie faktor viii-praeparation und verfahren zu ihrer herstellung
HUP9701554D0 (en) * 1997-09-18 1997-11-28 Human Oltoanyagtermeloe Gyogys Pharmaceutical composition containing plazma proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2826533A (en) * 1954-03-15 1958-03-11 Cutter Lab Stable fibrinogen solutions and method for producing same

Also Published As

Publication number Publication date
DE2653534A1 (de) 1977-06-30
CA1066189A (en) 1979-11-13
GB1540610A (en) 1979-02-14
ATA956676A (de) 1978-12-15
DE2653534C2 (de) 1986-08-28
AT351158B (de) 1979-07-10
JPS5282716A (en) 1977-07-11
MX4730E (es) 1982-08-24

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