Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co LtdfiledCriticalYamanouchi Pharmaceutical Co Ltd
Publication of ES450286A1publicationCriticalpatent/ES450286A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
A process for the production of a 6-p-hydroxyphenyl- α- (4-oxo-4h-thiopyran-3-ylcarboxamido) -acetic acid penicillanic acid of the formula: ** (see formula) ** And its non-toxic pharmaceutically acceptable salts, which process consists in reacting a 6-aminopenicillanic acid derivative represented by the formula: ** (see formula) ** Where r represents a hydrogen atom, an alkali metal atom or a residue etc. An organic ester that can be separated under mild conditions, or an ester thereof, with an acetic acid α -p-hydroxyphenyl- α-( 4-oxo-4h-thiopyran-3-yl-carboxamido), represented by the formula : ** (see formula) ** Or a reactive derivative thereof, and, if the r group is a residue of an organic ester that can be separated under mild conditions, separate said group. (Machine-translation by Google Translate, not legally binding)
A process of production of acid 6- (p-hydroxyphenyl- alpha- (4-oxo-4h-tiopiran-3-ilcarboxamido) acetamido) -penicilanico. (Machine-translation by Google Translate, not legally binding)
A procedure for the obtaining of new derivatives of the 6-amino-penicilanico acid and its salts. (Machine-translation by Google Translate, not legally binding)
New compounds constituted by the acid quinazolon-4-carboxilico-2, its salts, esters and other derivatives and its manufacturing procedure. (Machine-translation by Google Translate, not legally binding)