ES447989A1 - Procedimiento de obtencion de un nuevo compuesto fenoxilado. - Google Patents
Procedimiento de obtencion de un nuevo compuesto fenoxilado.Info
- Publication number
- ES447989A1 ES447989A1 ES447989A ES447989A ES447989A1 ES 447989 A1 ES447989 A1 ES 447989A1 ES 447989 A ES447989 A ES 447989A ES 447989 A ES447989 A ES 447989A ES 447989 A1 ES447989 A1 ES 447989A1
- Authority
- ES
- Spain
- Prior art keywords
- alclofenac
- antipyretic
- antiinflammatory
- analgesic
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ARHWPKZXBHOEEE-UHFFFAOYSA-N alclofenac Chemical compound OC(=O)CC1=CC=C(OCC=C)C(Cl)=C1 ARHWPKZXBHOEEE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960005142 alclofenac Drugs 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000001754 anti-pyretic effect Effects 0.000 title abstract 2
- 239000002221 antipyretic Substances 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 230000001988 toxicity Effects 0.000 title abstract 2
- 231100000419 toxicity Toxicity 0.000 title abstract 2
- VAXKNTYKFVYIFL-UHFFFAOYSA-N 2-[3-chloro-4-(cyclopropylmethoxy)phenyl]propanoic acid Chemical compound ClC1=CC(C(C(O)=O)C)=CC=C1OCC1CC1 VAXKNTYKFVYIFL-UHFFFAOYSA-N 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DEL ACIDO ALFA-(3-CLORO-4-CICLOPROPILMETILOXIFENIL) PROPIONICO Y SUS SALES DE ADICION NO TOXICAS. LA OBTENCION SE REALIZA MEDIANTE UNA SINTESIS EN OCHO PASOS PARTIENDO DEL (3-CLORO-4-METOXIFENIL) ACETONITRILO. COMO PRODUCTO INTERMEDIO SE OBTIENE EL ACIDO ALFA-(3-CLORO-HIDROXIFENIL) PROPIONICO, PARA EL QUE SE DESCRIBEN ADEMAS OTRAS DOS RUTAS DE SINTESIS DISTINTAS, LA PRIMERA PARTIENDO DEL (3-CLORO-4-METOXIFENIL) ACETONITRICO Y LA SEGUNDA DEL (3-CLORO-4-METOXIFENIL) ACETATO DE ALQUILO QUE SE OBTIENE COMO PRODUCTO INTERMEDIO EN EL PRIMER PASO DE LA SINTESIS A LA QUE SE HA HECHO REFERENCIA EN PRIMER LUGAR. EL ACIDO OBETENIDO PRESENTA PROPIEDADES ANTI-INFLAMATORIAS, ANALGESICAS Y ANTIPIRETICAS.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES447989A ES447989A1 (es) | 1976-05-10 | 1976-05-10 | Procedimiento de obtencion de un nuevo compuesto fenoxilado. |
FR7714274A FR2421612A1 (fr) | 1976-05-10 | 1977-05-10 | Medicament constitue par un derive de l'acide 2-phenyl-propionique et son procede de preparation |
DE19772721025 DE2721025A1 (de) | 1976-05-10 | 1977-05-10 | 2-phenyl-propionsaeurederivat, verfahren zu dessen herstellung und diese verbindung enthaltende pharmazeutische mittel |
BE177577A BE854632A (fr) | 1976-05-10 | 1977-05-13 | Derives de l'acide 2-phenyl-propionique et procede de preparation |
IT7919880A IT1202878B (it) | 1976-05-10 | 1979-02-05 | Derivato di acido 2-fenilpropionico e procedimento per la sua preparazione. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES447989A ES447989A1 (es) | 1976-05-10 | 1976-05-10 | Procedimiento de obtencion de un nuevo compuesto fenoxilado. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES447989A1 true ES447989A1 (es) | 1977-06-16 |
Family
ID=8471579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES447989A Expired ES447989A1 (es) | 1976-05-10 | 1976-05-10 | Procedimiento de obtencion de un nuevo compuesto fenoxilado. |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE854632A (es) |
DE (1) | DE2721025A1 (es) |
ES (1) | ES447989A1 (es) |
FR (1) | FR2421612A1 (es) |
IT (1) | IT1202878B (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE32439B1 (en) * | 1967-09-27 | 1973-08-08 | Madan Ag | Substituted phenylacetic acids and process of preparation thereof |
-
1976
- 1976-05-10 ES ES447989A patent/ES447989A1/es not_active Expired
-
1977
- 1977-05-10 FR FR7714274A patent/FR2421612A1/fr not_active Withdrawn
- 1977-05-10 DE DE19772721025 patent/DE2721025A1/de not_active Withdrawn
- 1977-05-13 BE BE177577A patent/BE854632A/xx unknown
-
1979
- 1979-02-05 IT IT7919880A patent/IT1202878B/it active
Also Published As
Publication number | Publication date |
---|---|
FR2421612A1 (fr) | 1979-11-02 |
BE854632A (fr) | 1977-09-01 |
IT7919880A0 (it) | 1979-02-05 |
IT1202878B (it) | 1989-02-15 |
DE2721025A1 (de) | 1977-12-01 |
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