ES446801A1 - Process for the stability of a macrolide antibiotic - Google Patents

Process for the stability of a macrolide antibiotic

Info

Publication number
ES446801A1
ES446801A1 ES446801A ES446801A ES446801A1 ES 446801 A1 ES446801 A1 ES 446801A1 ES 446801 A ES446801 A ES 446801A ES 446801 A ES446801 A ES 446801A ES 446801 A1 ES446801 A1 ES 446801A1
Authority
ES
Spain
Prior art keywords
macrolide antibiotic
stability
macrolide
translation
organic solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES446801A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Publication of ES446801A1 publication Critical patent/ES446801A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Process for preparing amorphous solids of macrolide antibiotics, which are stable over time, characterized in that it comprises spray drying a solution in a volatile organic solvent of a macrolide antibiotic and at least one cellulose polymer. (Machine-translation by Google Translate, not legally binding)
ES446801A 1975-04-08 1976-04-08 Process for the stability of a macrolide antibiotic Expired ES446801A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4182275A JPS51118816A (en) 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid

Publications (1)

Publication Number Publication Date
ES446801A1 true ES446801A1 (en) 1977-06-01

Family

ID=12618972

Family Applications (1)

Application Number Title Priority Date Filing Date
ES446801A Expired ES446801A1 (en) 1975-04-08 1976-04-08 Process for the stability of a macrolide antibiotic

Country Status (8)

Country Link
JP (1) JPS51118816A (en)
CA (1) CA1063936A (en)
DE (1) DE2615403C2 (en)
ES (1) ES446801A1 (en)
FR (1) FR2306705A1 (en)
GB (1) GB1534070A (en)
MX (1) MX3401E (en)
NL (1) NL176270C (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5819844B2 (en) * 1978-07-13 1983-04-20 三菱自動車工業株式会社 Engine fuel supply system
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS56103109A (en) * 1979-08-31 1981-08-18 Eisai Co Ltd Ubidecarenone-containing composition having improved dispersion properties
FR2525108B1 (en) * 1982-04-19 1989-05-12 Elan Corp Ltd HIGH-SOLUBILITY MEDICINES AND PROCESS FOR OBTAINING THEM
US4767789A (en) * 1986-10-21 1988-08-30 American Home Products Corporation (Del.) Spray dried acetaminophen
GB9713730D0 (en) * 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers

Also Published As

Publication number Publication date
GB1534070A (en) 1978-11-29
NL7603635A (en) 1976-10-12
MX3401E (en) 1980-10-30
JPS51118816A (en) 1976-10-19
NL176270B (en) 1984-10-16
JPS5545042B2 (en) 1980-11-15
FR2306705A1 (en) 1976-11-05
DE2615403A1 (en) 1976-10-28
DE2615403C2 (en) 1982-07-15
NL176270C (en) 1985-03-18
FR2306705B1 (en) 1980-07-18
CA1063936A (en) 1979-10-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970218