ES445395A1 - Production of acetylsalycylic acid derivatives and antiipyretic * lenitive and antiiinflammatory agent containing the same - Google Patents

Production of acetylsalycylic acid derivatives and antiipyretic * lenitive and antiiinflammatory agent containing the same

Info

Publication number
ES445395A1
ES445395A1 ES445395A ES445395A ES445395A1 ES 445395 A1 ES445395 A1 ES 445395A1 ES 445395 A ES445395 A ES 445395A ES 445395 A ES445395 A ES 445395A ES 445395 A1 ES445395 A1 ES 445395A1
Authority
ES
Spain
Prior art keywords
proline
antiipyretic
antiiinflammatory
acetylsalycylic
lenitive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES445395A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of ES445395A1 publication Critical patent/ES445395A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

A process for the preparation of 1-o-acetoxybenzoyl-4-hydroxy-l-proline and 1-0-acetoxybenzoyl-l-proline, characterized in that suitable amounts of acetylsalicylic acid or one of its halides are reacted with a product selected from l -proline and 4-hydroxy-l-proline, the reaction taking place in solution in an aqueous, neutral or slightly basic organic medium, precipitating the product obtained by acidulation of said medium and separating said precipitate from the reaction medium. (Machine-translation by Google Translate, not legally binding)
ES445395A 1975-06-02 1976-02-20 Production of acetylsalycylic acid derivatives and antiipyretic * lenitive and antiiinflammatory agent containing the same Expired ES445395A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7517140A FR2346015A2 (en) 1975-06-02 1975-06-02 L-Proline derivs of acetyl salicylic acid - analgesics, antiinflammatories and antithermics, free from ulcerogenic activity

Publications (1)

Publication Number Publication Date
ES445395A1 true ES445395A1 (en) 1977-06-01

Family

ID=9155944

Family Applications (1)

Application Number Title Priority Date Filing Date
ES445395A Expired ES445395A1 (en) 1975-06-02 1976-02-20 Production of acetylsalycylic acid derivatives and antiipyretic * lenitive and antiiinflammatory agent containing the same

Country Status (6)

Country Link
JP (1) JPS6011693B2 (en)
BE (1) BE839102A (en)
DD (1) DD124381A5 (en)
DE (1) DE2607627A1 (en)
ES (1) ES445395A1 (en)
FR (1) FR2346015A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4987042A (en) * 1972-12-26 1974-08-20
JPS6437398U (en) * 1987-08-28 1989-03-07
US20080102042A1 (en) * 2004-10-28 2008-05-01 Kyowa Hakko Kogyo Co., Ltd. Oral Composition

Also Published As

Publication number Publication date
DE2607627A1 (en) 1976-12-23
BE839102A (en) 1976-07-01
JPS6011693B2 (en) 1985-03-27
FR2346015B2 (en) 1979-01-05
FR2346015A2 (en) 1977-10-28
JPS525759A (en) 1977-01-17
DD124381A5 (en) 1977-02-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980203