ES444346A1 - Procedure for obtaining new acilefalosporines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining new acilefalosporines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES444346A1
ES444346A1 ES444346A ES444346A ES444346A1 ES 444346 A1 ES444346 A1 ES 444346A1 ES 444346 A ES444346 A ES 444346A ES 444346 A ES444346 A ES 444346A ES 444346 A1 ES444346 A1 ES 444346A1
Authority
ES
Spain
Prior art keywords
translation
procedure
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES444346A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Cusi SA
Original Assignee
Laboratorios Cusi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Cusi SA filed Critical Laboratorios Cusi SA
Priority to ES444346A priority Critical patent/ES444346A1/en
Priority to DE2657652A priority patent/DE2657652C3/en
Publication of ES444346A1 publication Critical patent/ES444346A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"PROCEDURE FOR OBTAINING NEW ACILEFALOSPORINS", characterized essentially because it consists of separately obtaining 7-ACA, 7-ADCA, cephalexin and substituted 7-ACA-3 acids, dissolving them or suspending them in an aqueous or organic aqueous medium, adding an ion scavenger hydrogen to react the set with acrylic acids -3- substituted in their reactive forms, the reaction temperature being between -30 and 70º C while its duration is a function of the permanence of the reagents, making the control of the course of the reaction by conventional means until a basic solution is obtained which is acidified with inorganic acids and finally extracted with an organic solvent from which the final product is isolated by evaporation. (Machine-translation by Google Translate, not legally binding)
ES444346A 1976-01-15 1976-01-15 Procedure for obtaining new acilefalosporines. (Machine-translation by Google Translate, not legally binding) Expired ES444346A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES444346A ES444346A1 (en) 1976-01-15 1976-01-15 Procedure for obtaining new acilefalosporines. (Machine-translation by Google Translate, not legally binding)
DE2657652A DE2657652C3 (en) 1976-01-15 1976-12-20 N-acyl derivatives of cefalexin and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES444346A ES444346A1 (en) 1976-01-15 1976-01-15 Procedure for obtaining new acilefalosporines. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES444346A1 true ES444346A1 (en) 1977-10-01

Family

ID=8470734

Family Applications (1)

Application Number Title Priority Date Filing Date
ES444346A Expired ES444346A1 (en) 1976-01-15 1976-01-15 Procedure for obtaining new acilefalosporines. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
DE (1) DE2657652C3 (en)
ES (1) ES444346A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1022544A (en) * 1972-12-21 1977-12-13 Yukiyasu Murakami Process of preparing a heterocyclic acyl group-substituted cephalosporin derivative

Also Published As

Publication number Publication date
DE2657652C3 (en) 1982-04-08
DE2657652B2 (en) 1981-04-23
DE2657652A1 (en) 1977-07-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202