ES443190A1 - Preparation of a semi-synthetic penicillin - Google Patents

Preparation of a semi-synthetic penicillin

Info

Publication number
ES443190A1
ES443190A1 ES443190A ES443190A ES443190A1 ES 443190 A1 ES443190 A1 ES 443190A1 ES 443190 A ES443190 A ES 443190A ES 443190 A ES443190 A ES 443190A ES 443190 A1 ES443190 A1 ES 443190A1
Authority
ES
Spain
Prior art keywords
dimethylphenam
alpha
preparation
semi
aminophenylacetamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES443190A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of ES443190A1 publication Critical patent/ES443190A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for the preparation of 6- (alpha-aminophenylacetamido) 2,2-dimethylphenam-3-carboxylic acid ** (See formula) ** wherein the asterisk-labeled carbon atom represents a center of asymmetry of the molecule as such or in the form of independent epimers, characterized in that the acid 6- (alpha-hydrazinophenylacetamido) 2,2-dimethylphenam-3 is subjected to catalytic reduction -carboxylic. ** (See formula) ** wherein the asterisk-labeled carbon atom has the aforementioned, previously protected meaning, and because 6- (alpha-aminophenylacetamido) 2,2-dimethylphenam-3-carboxylic acid is isolated in a known manner as is or in the form of independent epimers. (Machine-translation by Google Translate, not legally binding)
ES443190A 1974-12-05 1975-12-04 Preparation of a semi-synthetic penicillin Expired ES443190A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT3018874 1974-12-05

Publications (1)

Publication Number Publication Date
ES443190A1 true ES443190A1 (en) 1977-08-16

Family

ID=11229285

Family Applications (1)

Application Number Title Priority Date Filing Date
ES443190A Expired ES443190A1 (en) 1974-12-05 1975-12-04 Preparation of a semi-synthetic penicillin

Country Status (6)

Country Link
JP (1) JPS5182287A (en)
DE (1) DE2554567A1 (en)
ES (1) ES443190A1 (en)
FR (1) FR2293434A1 (en)
GB (1) GB1463270A (en)
NL (1) NL7513996A (en)

Also Published As

Publication number Publication date
DE2554567A1 (en) 1976-06-10
JPS5182287A (en) 1976-07-19
NL7513996A (en) 1976-06-09
GB1463270A (en) 1977-02-02
FR2293434B1 (en) 1978-05-12
FR2293434A1 (en) 1976-07-02

Similar Documents

Publication Publication Date Title
ES452942A1 (en) Dihydrocyclosporin c
ES438946A2 (en) Vincaminic acid esters
ES432334A1 (en) 11 amidoarukiru 44 suruhoniruupiperajinkagobutsunoseizoho
ES404745A1 (en) Cephalosporin compounds
ES443190A1 (en) Preparation of a semi-synthetic penicillin
ES423699A1 (en) 3-oxyiminomethyl-cephalosporins
ES404315A1 (en) Nitrosourea derivatives
ES443191A1 (en) Preparation of a semi-synthetic cephalosporin
ES462844A1 (en) Compound and production thereof
ES433723A1 (en) Procedure for obtaining a derivative of 2-pirrolidinone. (Machine-translation by Google Translate, not legally binding)
GB1467528A (en) Piperazinium 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolyl acetate
ES400623A1 (en) Pharmaceutical compositions
ES407018A1 (en) Dialkylsulfoximinocarbonylmethyl thiophosphates and process for preparation thereof
ES386714A1 (en) Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)
ES409555A1 (en) A procedure for the obtaining of new derivatives of cefalosporine. (Machine-translation by Google Translate, not legally binding)
ES477051A1 (en) Novel compound
ES438725A1 (en) Prostadienoic acid derivatives
ES429817A1 (en) 6-trichloroacetamido-penicillanic acid derivatives and their preparation
ES398868A1 (en) Process for the preparation of derivatives of 1,2-diphenyl-3,5- dioxo-4-n-butylpyrazolidine
ES388250A1 (en) A procedure for preparing pirazolo-piridincarboxilico acid compounds. (Machine-translation by Google Translate, not legally binding)
ES289923A1 (en) Procedure for the production of verrucarine derivatives (Machine-translation by Google Translate, not legally binding)
ES398377A1 (en) Procedure for obtaining di- (N-metilcarbamate) from bis 2.6 (hydroxymethyl) -piridine. (Machine-translation by Google Translate, not legally binding)
ES458784A1 (en) Thiophene derivatives and process for preparation thereof
ES431477A1 (en) Procedure for preparing glycerol derivatives. (Machine-translation by Google Translate, not legally binding)
ES315330A1 (en) Procedure for the monohydration of the equimolecular complex formed by ascorbic acid and pyridoxine. (Machine-translation by Google Translate, not legally binding)