ES440584A1 - Benzothiazolyl ureas and pharmaceutical compositions containing them - Google Patents

Benzothiazolyl ureas and pharmaceutical compositions containing them

Info

Publication number
ES440584A1
ES440584A1 ES440584A ES440584A ES440584A1 ES 440584 A1 ES440584 A1 ES 440584A1 ES 440584 A ES440584 A ES 440584A ES 440584 A ES440584 A ES 440584A ES 440584 A1 ES440584 A1 ES 440584A1
Authority
ES
Spain
Prior art keywords
formula
ureas
benzothiazolyl
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES440584A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/502,130 external-priority patent/US3932435A/en
Priority claimed from US05/502,129 external-priority patent/US3932434A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES440584A1 publication Critical patent/ES440584A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A process for the preparation of N-2- (6-hydroxybenzothiazolyl) -N'-phenyl (or substituted phenyl) -ureas compounds of formula: **(See formula)** wherein R is hydrogen, (C1-C3) alkyl, (C1-C3) alkoxy or halo, characterized by reacting a benzothiazole of the formula **(See formula)** with a substituted phenyl compound of formula **(See formula)** where R is hydrogen, (C1-C3) alkyl, (C1-C3) alkoxy or halo; and hydrolyze the resulting compound. (Machine-translation by Google Translate, not legally binding)
ES440584A 1974-08-30 1975-08-29 Benzothiazolyl ureas and pharmaceutical compositions containing them Expired ES440584A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/502,130 US3932435A (en) 1974-08-30 1974-08-30 Preparation of N-2-(6-hydroxybenzothiazolyl)-N'-phenyl (or substituted-phenyl) ureas
US05/502,129 US3932434A (en) 1974-08-30 1974-08-30 N-2-(6-hydroxybenzothiazolyl)-N'-phenyl (or substituted phenyl) ureas

Publications (1)

Publication Number Publication Date
ES440584A1 true ES440584A1 (en) 1977-05-16

Family

ID=27054031

Family Applications (1)

Application Number Title Priority Date Filing Date
ES440584A Expired ES440584A1 (en) 1974-08-30 1975-08-29 Benzothiazolyl ureas and pharmaceutical compositions containing them

Country Status (17)

Country Link
AR (2) AR206720A1 (en)
AT (1) AT344189B (en)
BG (1) BG23003A3 (en)
DD (1) DD122250A5 (en)
DE (1) DE2537777A1 (en)
DK (1) DK389875A (en)
ES (1) ES440584A1 (en)
FR (1) FR2282883A1 (en)
GB (1) GB1516857A (en)
HU (1) HU174132B (en)
IE (1) IE41459B1 (en)
IL (1) IL47963A (en)
NL (1) NL7510203A (en)
PL (1) PL108429B1 (en)
RO (1) RO65771A (en)
SE (1) SE415099B (en)
SU (2) SU617013A3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101116627B1 (en) 2002-06-27 2012-10-09 노보 노르디스크 에이/에스 Aryl carbonyl derivatives as therapeutic agents

Also Published As

Publication number Publication date
DD122250A5 (en) 1976-09-20
AR206720A1 (en) 1976-08-13
AU8418575A (en) 1977-02-24
IL47963A0 (en) 1975-11-25
HU174132B (en) 1979-11-28
IE41459L (en) 1976-02-29
FR2282883B1 (en) 1979-09-14
DK389875A (en) 1976-03-01
AT344189B (en) 1978-07-10
NL7510203A (en) 1976-03-02
SU895290A3 (en) 1981-12-30
GB1516857A (en) 1978-07-05
SE7509436L (en) 1976-03-01
IL47963A (en) 1978-07-31
SE415099B (en) 1980-09-08
DE2537777A1 (en) 1976-03-11
BG23003A3 (en) 1977-05-20
FR2282883A1 (en) 1976-03-26
IE41459B1 (en) 1980-01-02
SU617013A3 (en) 1978-07-25
ATA669175A (en) 1977-11-15
PL108429B1 (en) 1980-04-30
AR209974A1 (en) 1977-06-15
RO65771A (en) 1979-08-15

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