ES437787A1 - A procedure for the preparation of a live virus atenuado de varicela. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of a live virus atenuado de varicela. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES437787A1
ES437787A1 ES437787A ES437787A ES437787A1 ES 437787 A1 ES437787 A1 ES 437787A1 ES 437787 A ES437787 A ES 437787A ES 437787 A ES437787 A ES 437787A ES 437787 A1 ES437787 A1 ES 437787A1
Authority
ES
Spain
Prior art keywords
virus
preparation
translation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437787A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority to ES437787A priority Critical patent/ES437787A1/en
Publication of ES437787A1 publication Critical patent/ES437787A1/en
Expired legal-status Critical Current

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A method for the preparation of a live attenuated varicella virus, free of cells, useful as an antigen in a vaccine, which evokes in man an antibody response against a virulent varicella virus without producing the serious clinical manifestations of the disease, whose procedure consists of serially passing the virulent virus at 30-38ºC in a tissue culture preparation selected from the group consisting of strains of animal and human diploid cells and primary cells of simian origin, a sufficient number of times to attenuate the virus, followed of release of the attenuated virus from the infected cells by sonification in the presence of a stabilizer. (Machine-translation by Google Translate, not legally binding)
ES437787A 1975-05-19 1975-05-19 A procedure for the preparation of a live virus atenuado de varicela. (Machine-translation by Google Translate, not legally binding) Expired ES437787A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES437787A ES437787A1 (en) 1975-05-19 1975-05-19 A procedure for the preparation of a live virus atenuado de varicela. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES437787A ES437787A1 (en) 1975-05-19 1975-05-19 A procedure for the preparation of a live virus atenuado de varicela. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES437787A1 true ES437787A1 (en) 1977-05-16

Family

ID=8469332

Family Applications (1)

Application Number Title Priority Date Filing Date
ES437787A Expired ES437787A1 (en) 1975-05-19 1975-05-19 A procedure for the preparation of a live virus atenuado de varicela. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES437787A1 (en)

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