ES436132A1 - Procedimiento para la preparacion de compuestos polimericos de la silibina. - Google Patents
Procedimiento para la preparacion de compuestos polimericos de la silibina.Info
- Publication number
- ES436132A1 ES436132A1 ES436132A ES436132A ES436132A1 ES 436132 A1 ES436132 A1 ES 436132A1 ES 436132 A ES436132 A ES 436132A ES 436132 A ES436132 A ES 436132A ES 436132 A1 ES436132 A1 ES 436132A1
- Authority
- ES
- Spain
- Prior art keywords
- silybin
- polymers
- therapeutic compositions
- oligomers
- condenses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FDQAOULAVFHKBX-UHFFFAOYSA-N Isosilybin A Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC(=CC=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 FDQAOULAVFHKBX-UHFFFAOYSA-N 0.000 title abstract 3
- SEBFKMXJBCUCAI-UHFFFAOYSA-N NSC 227190 Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC=C(C=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-UHFFFAOYSA-N 0.000 title abstract 3
- VLGROHBNWZUINI-UHFFFAOYSA-N Silybin Natural products COc1cc(ccc1O)C2OC3C=C(C=CC3OC2CO)C4Oc5cc(O)cc(O)c5C(=O)C4O VLGROHBNWZUINI-UHFFFAOYSA-N 0.000 title abstract 3
- SEBFKMXJBCUCAI-HKTJVKLFSA-N silibinin Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 title abstract 3
- 229940043175 silybin Drugs 0.000 title abstract 3
- 235000014899 silybin Nutrition 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19742416302 DE2416302B2 (de) | 1974-04-04 | 1974-04-04 | Dimeres sowie trimeres silybin und deren n-methylglucaminsalz und verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES436132A1 true ES436132A1 (es) | 1977-02-01 |
Family
ID=5912093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES436132A Expired ES436132A1 (es) | 1974-04-04 | 1975-03-29 | Procedimiento para la preparacion de compuestos polimericos de la silibina. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3997671A (OSRAM) |
| JP (1) | JPS5314074B2 (OSRAM) |
| AR (1) | AR203502A1 (OSRAM) |
| AT (1) | AT340418B (OSRAM) |
| BE (1) | BE827512A (OSRAM) |
| CA (1) | CA1047509A (OSRAM) |
| CH (1) | CH611293A5 (OSRAM) |
| DE (1) | DE2416302B2 (OSRAM) |
| ES (1) | ES436132A1 (OSRAM) |
| FI (1) | FI62536C (OSRAM) |
| FR (1) | FR2266513B1 (OSRAM) |
| GB (1) | GB1501429A (OSRAM) |
| IT (1) | IT1060377B (OSRAM) |
| NL (1) | NL159103B (OSRAM) |
| ZA (1) | ZA752134B (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1554662A (en) * | 1976-05-05 | 1979-10-24 | Inverni Della Beffa Spa | Polyhydroxyphenylchromanones |
| DE3537656A1 (de) * | 1984-11-22 | 1986-05-22 | Dr. Madaus GmbH & Co, 5000 Köln | Verfahren zur herstellung von isosilybinfreiem silibinin und arzneimittel, enthaltend silibinin |
| US6913769B2 (en) * | 2003-02-18 | 2005-07-05 | Brian Douglas Oslick | Compositions for prevention and treatment of symptoms associated with ethyl alcohol consumption |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1963318A1 (de) * | 1969-12-17 | 1971-06-24 | Schwabe Willmar Gmbh & Co | Silybinhalbester der Bernsteinsaeure und der Phthalsaeure,ihre Salze mit pharmakologisch vertraglichen Basen,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten |
-
1974
- 1974-04-04 DE DE19742416302 patent/DE2416302B2/de active Granted
-
1975
- 1975-03-14 FI FI750735A patent/FI62536C/fi not_active IP Right Cessation
- 1975-03-17 AT AT202075A patent/AT340418B/de not_active IP Right Cessation
- 1975-03-28 IT IT21814/75A patent/IT1060377B/it active
- 1975-03-29 ES ES436132A patent/ES436132A1/es not_active Expired
- 1975-03-31 AR AR258172A patent/AR203502A1/es active
- 1975-04-02 CH CH417475A patent/CH611293A5/xx not_active IP Right Cessation
- 1975-04-03 FR FR7510475A patent/FR2266513B1/fr not_active Expired
- 1975-04-03 BE BE155046A patent/BE827512A/xx unknown
- 1975-04-03 JP JP4076975A patent/JPS5314074B2/ja not_active Expired
- 1975-04-03 GB GB13671/75A patent/GB1501429A/en not_active Expired
- 1975-04-03 NL NL7503960.A patent/NL159103B/xx not_active IP Right Cessation
- 1975-04-03 CA CA223,759A patent/CA1047509A/en not_active Expired
- 1975-04-04 US US05/565,175 patent/US3997671A/en not_active Expired - Lifetime
- 1975-04-04 ZA ZA00752134A patent/ZA752134B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5191272A (OSRAM) | 1976-08-10 |
| US3997671A (en) | 1976-12-14 |
| AR203502A1 (es) | 1975-09-15 |
| FI62536C (fi) | 1983-01-10 |
| DE2416302C3 (OSRAM) | 1978-10-05 |
| CH611293A5 (OSRAM) | 1979-05-31 |
| FR2266513A1 (OSRAM) | 1975-10-31 |
| FR2266513B1 (OSRAM) | 1979-08-10 |
| IT1060377B (it) | 1982-07-10 |
| JPS5314074B2 (OSRAM) | 1978-05-15 |
| AT340418B (de) | 1977-12-12 |
| NL7503960A (nl) | 1975-10-07 |
| ATA202075A (de) | 1977-04-15 |
| CA1047509A (en) | 1979-01-30 |
| NL159103B (nl) | 1979-01-15 |
| FI62536B (fi) | 1982-09-30 |
| BE827512A (fr) | 1975-10-03 |
| GB1501429A (en) | 1978-02-15 |
| FI750735A7 (OSRAM) | 1975-10-05 |
| ZA752134B (en) | 1976-04-28 |
| DE2416302A1 (de) | 1976-01-22 |
| DE2416302B2 (de) | 1978-02-02 |
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