ES435739A1 - A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES435739A1
ES435739A1 ES435739A ES435739A ES435739A1 ES 435739 A1 ES435739 A1 ES 435739A1 ES 435739 A ES435739 A ES 435739A ES 435739 A ES435739 A ES 435739A ES 435739 A1 ES435739 A1 ES 435739A1
Authority
ES
Spain
Prior art keywords
anomers
beta
daunomycin
translation
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES435739A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of ES435739A1 publication Critical patent/ES435739A1/en
Expired legal-status Critical Current

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Abstract

A process for the preparation of daunomycin, 4'-epidaunomycin, and respective beta-anomers characterized in that it comprises reacting daunomycinone with a 1-chloro-2,3,6-trideoxy-3-trifluoro-acetamido-4-trifluoroacetoxy-hexose, having an l-lixo or l-arabino configuration, in an appropriate organic solvent in the presence of a mercuric salt as a catalyst and as an appropriate acceptor of hydrogen chloride and then separating the protective trifluoroacetyl groups from the glycosidic compounds formed and separation of the alpha and beta anomers. (Machine-translation by Google Translate, not legally binding)
ES435739A 1974-03-20 1975-03-18 A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding) Expired ES435739A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1225474 1974-03-20

Publications (1)

Publication Number Publication Date
ES435739A1 true ES435739A1 (en) 1976-12-16

Family

ID=11139633

Family Applications (1)

Application Number Title Priority Date Filing Date
ES435739A Expired ES435739A1 (en) 1974-03-20 1975-03-18 A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES435739A1 (en)

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