ES435739A1 - A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding)
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Pfizer Italia SRL
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Farmaceutici Italia SpA
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Publication of ES435739A1publicationCriticalpatent/ES435739A1/en
A process for the preparation of daunomycin, 4'-epidaunomycin, and respective beta-anomers characterized in that it comprises reacting daunomycinone with a 1-chloro-2,3,6-trideoxy-3-trifluoro-acetamido-4-trifluoroacetoxy-hexose, having an l-lixo or l-arabino configuration, in an appropriate organic solvent in the presence of a mercuric salt as a catalyst and as an appropriate acceptor of hydrogen chloride and then separating the protective trifluoroacetyl groups from the glycosidic compounds formed and separation of the alpha and beta anomers. (Machine-translation by Google Translate, not legally binding)
ES435739A1974-03-201975-03-18A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding)
ExpiredES435739A1
(en)
A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of daunomycin, 4'-e-pidaunomycin and beta-respective anomers. (Machine-translation by Google Translate, not legally binding)