ES431312A1 - Procedimiento de preparacion de nuevos derivados de la fe- nil propenilamina. - Google Patents
Procedimiento de preparacion de nuevos derivados de la fe- nil propenilamina.Info
- Publication number
- ES431312A1 ES431312A1 ES431312A ES431312A ES431312A1 ES 431312 A1 ES431312 A1 ES 431312A1 ES 431312 A ES431312 A ES 431312A ES 431312 A ES431312 A ES 431312A ES 431312 A1 ES431312 A1 ES 431312A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- ch2ch2
- alkyl group
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- CDZOGLJOFWFVOZ-UHFFFAOYSA-N n-propylaniline Chemical class CCCNC1=CC=CC=C1 CDZOGLJOFWFVOZ-UHFFFAOYSA-N 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- MUMZUERVLWJKNR-UHFFFAOYSA-N oxoplatinum Chemical compound [Pt]=O MUMZUERVLWJKNR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229910003446 platinum oxide Inorganic materials 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5112373A GB1475314A (en) | 1973-11-02 | 1973-11-02 | Phenyl-propylamine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES431312A1 true ES431312A1 (es) | 1976-10-16 |
Family
ID=10458750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES431312A Expired ES431312A1 (es) | 1973-11-02 | 1974-10-24 | Procedimiento de preparacion de nuevos derivados de la fe- nil propenilamina. |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5077351A (cs) |
| AT (1) | AT337165B (cs) |
| BE (1) | BE821571A (cs) |
| CA (1) | CA1045137A (cs) |
| CH (1) | CH593907A5 (cs) |
| DD (1) | DD115110A5 (cs) |
| DE (1) | DE2451474A1 (cs) |
| DK (1) | DK570374A (cs) |
| ES (1) | ES431312A1 (cs) |
| FR (1) | FR2249659B1 (cs) |
| GB (1) | GB1475314A (cs) |
| HU (1) | HU172221B (cs) |
| NL (1) | NL7414310A (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4690979A (en) * | 1978-05-16 | 1979-11-29 | F. Hoffmann-La Roche Ag | Heterocyclic compounds |
| IL59557A (en) * | 1979-03-12 | 1983-10-31 | Lilly Co Eli | 1,1-biphenyl-2-yl propyl butyl and pentyl amines,their preparation and pharmaceutical compositions comprising them |
| IT1113391B (it) * | 1979-05-09 | 1986-01-20 | Maggioni Farma | Derivati fenilcicloesanici ad attivita' antidepressiva |
| FR2641276B1 (fr) * | 1988-12-30 | 1991-07-12 | Sanofi Sa | Derives du benzene, leur preparation et les compositions pharmaceutiques en contenant |
| FR2663328B1 (fr) | 1990-06-14 | 1994-08-05 | Sanofi Sa | Derives d'hexahydroazepines, un procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2751645B1 (fr) | 1996-07-29 | 1998-12-24 | Sanofi Sa | Amines pour la fabrication de medicaments destines a empecher la proliferation de cellules tumorales |
| IT1304874B1 (it) * | 1998-07-17 | 2001-04-05 | Univ Firenze | Amminoalcoli,amminochetoni e loro derivati,loro preparazione ed usocome farmaci per le patologie del sistema nervoso centrale (snc) e |
| FR2795724B1 (fr) * | 1999-07-02 | 2002-12-13 | Sanofi Synthelabo | Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
| DE102006031813B4 (de) * | 2006-07-07 | 2011-04-28 | Christian-Albrechts-Universität Zu Kiel | Verwendung basischer Acetophenone als Hemmstoffe von NO-Synthasen |
| JP2023541960A (ja) | 2020-09-17 | 2023-10-04 | メレティオス セラピューティクス | ウイルス感染を治療するための化合物 |
-
1973
- 1973-11-02 GB GB5112373A patent/GB1475314A/en not_active Expired
-
1974
- 1974-10-09 FR FR7433989A patent/FR2249659B1/fr not_active Expired
- 1974-10-21 CA CA211,894A patent/CA1045137A/en not_active Expired
- 1974-10-24 ES ES431312A patent/ES431312A1/es not_active Expired
- 1974-10-28 AT AT866574A patent/AT337165B/de not_active IP Right Cessation
- 1974-10-29 BE BE2053947A patent/BE821571A/xx unknown
- 1974-10-30 DE DE19742451474 patent/DE2451474A1/de not_active Withdrawn
- 1974-10-31 DD DD18206974A patent/DD115110A5/xx unknown
- 1974-10-31 HU HU74CE00001023A patent/HU172221B/hu unknown
- 1974-11-01 DK DK570374A patent/DK570374A/da unknown
- 1974-11-01 NL NL7414310A patent/NL7414310A/xx not_active Application Discontinuation
- 1974-11-01 CH CH1469574A patent/CH593907A5/xx not_active IP Right Cessation
- 1974-11-02 JP JP12702474A patent/JPS5077351A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HU172221B (hu) | 1978-07-28 |
| FR2249659B1 (cs) | 1978-03-24 |
| DE2451474A1 (de) | 1975-05-07 |
| DD115110A5 (cs) | 1975-09-12 |
| DK570374A (cs) | 1975-06-23 |
| CA1045137A (en) | 1978-12-26 |
| NL7414310A (nl) | 1975-05-07 |
| AT337165B (de) | 1977-06-10 |
| BE821571A (fr) | 1975-02-17 |
| CH593907A5 (cs) | 1977-12-30 |
| GB1475314A (en) | 1977-06-01 |
| FR2249659A1 (cs) | 1975-05-30 |
| JPS5077351A (cs) | 1975-06-24 |
| ATA866574A (de) | 1976-10-15 |
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