ES419868A1 - Procedimiento para la preparacion de un complejo de codeinay 6-amino-2-metil-heptan-2-ol. - Google Patents
Procedimiento para la preparacion de un complejo de codeinay 6-amino-2-metil-heptan-2-ol.Info
- Publication number
- ES419868A1 ES419868A1 ES419868A ES419868A ES419868A1 ES 419868 A1 ES419868 A1 ES 419868A1 ES 419868 A ES419868 A ES 419868A ES 419868 A ES419868 A ES 419868A ES 419868 A1 ES419868 A1 ES 419868A1
- Authority
- ES
- Spain
- Prior art keywords
- codeine
- production
- cough medicine
- heptan
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 206010011224 Cough Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 abstract 3
- LREQLEBVOXIEOM-UHFFFAOYSA-N 6-amino-2-methyl-2-heptanol Chemical compound CC(N)CCCC(C)(C)O LREQLEBVOXIEOM-UHFFFAOYSA-N 0.000 abstract 2
- DKSZLDSPXIWGFO-BLOJGBSASA-N (4r,4ar,7s,7ar,12bs)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol;phosphoric acid;hydrate Chemical compound O.OP(O)(O)=O.OP(O)(O)=O.C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC.C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC DKSZLDSPXIWGFO-BLOJGBSASA-N 0.000 abstract 1
- DYXBSXBXZNSAPO-UHFFFAOYSA-M 1,1-dimethylpyrrolidin-1-ium;iodide Chemical compound [I-].C[N+]1(C)CCCC1 DYXBSXBXZNSAPO-UHFFFAOYSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229960004126 codeine Drugs 0.000 abstract 1
- 229960001012 codeine hydrochloride Drugs 0.000 abstract 1
- 229960004415 codeine phosphate Drugs 0.000 abstract 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1673972 | 1972-11-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES419868A1 true ES419868A1 (es) | 1976-08-01 |
Family
ID=4419797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES419868A Expired ES419868A1 (es) | 1972-11-16 | 1973-10-23 | Procedimiento para la preparacion de un complejo de codeinay 6-amino-2-metil-heptan-2-ol. |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT330344B (enrdf_load_html_response) |
| BE (1) | BE807454A (enrdf_load_html_response) |
| ES (1) | ES419868A1 (enrdf_load_html_response) |
| FR (1) | FR2206940B1 (enrdf_load_html_response) |
| GB (1) | GB1388099A (enrdf_load_html_response) |
| IL (1) | IL43569A (enrdf_load_html_response) |
| NL (1) | NL147936B (enrdf_load_html_response) |
| SE (1) | SE419162B (enrdf_load_html_response) |
-
1973
- 1973-10-17 AT AT880573A patent/AT330344B/de not_active IP Right Cessation
- 1973-10-23 ES ES419868A patent/ES419868A1/es not_active Expired
- 1973-10-23 GB GB4936473A patent/GB1388099A/en not_active Expired
- 1973-11-05 IL IL43569A patent/IL43569A/en unknown
- 1973-11-06 SE SE7315057A patent/SE419162B/xx unknown
- 1973-11-09 NL NL737315355A patent/NL147936B/xx not_active IP Right Cessation
- 1973-11-15 FR FR7340722A patent/FR2206940B1/fr not_active Expired
- 1973-11-16 BE BE137870A patent/BE807454A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BE807454A (fr) | 1974-03-15 |
| ATA880573A (de) | 1975-09-15 |
| GB1388099A (en) | 1975-03-19 |
| AT330344B (de) | 1976-06-25 |
| IL43569A (en) | 1976-01-30 |
| DE2349157B2 (de) | 1977-04-14 |
| IL43569A0 (en) | 1974-03-14 |
| FR2206940B1 (enrdf_load_html_response) | 1977-08-19 |
| NL147936B (nl) | 1975-12-15 |
| NL7315355A (enrdf_load_html_response) | 1974-05-20 |
| SE419162B (sv) | 1981-07-20 |
| FR2206940A1 (enrdf_load_html_response) | 1974-06-14 |
| DE2349157A1 (de) | 1974-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19920213 |