ES418666A1 - (2-(2-methyl-5-nitro-1-imidazolyl)ethyl)heteroaryloxy ethers - Google Patents
(2-(2-methyl-5-nitro-1-imidazolyl)ethyl)heteroaryloxy ethersInfo
- Publication number
- ES418666A1 ES418666A1 ES418666A ES418666A ES418666A1 ES 418666 A1 ES418666 A1 ES 418666A1 ES 418666 A ES418666 A ES 418666A ES 418666 A ES418666 A ES 418666A ES 418666 A1 ES418666 A1 ES 418666A1
- Authority
- ES
- Spain
- Prior art keywords
- nitro
- formula
- methyl
- heteroaryloxy
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 2-(2-methyl-5-nitro-1-imidazolyl)ethyl Chemical group 0.000 title 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000005553 heteroaryloxy group Chemical group 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 125000005948 methanesulfonyloxy group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of 2-methyl-5-nitro-1- [2- (heteroaryloxy) ethyl] imidazoles, of general formula: **(See formula)** wherein R is a pyridyl or benzo (b) pyridyl radical, optionally substituted with one or more nitro, halogen or methyl groups, with a maximum of three substituents, characterized in that a compound of the general formula is reacted: **(See formula)** where A is a hydrogen atom or a radical of the formula -CH2CH2X where X is halogen, toluenesulfonyloxy or methanesulfonyloxy; with a compound of general formula: BR (III) where R is defined as above and B is an alkali metal oxy group, when A is -CH2CH2X, or B is a radical of the formula -OCH2CH2X, where X is defined as above, when A is a hydrogen atom . (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00288111A US3828056A (en) | 1972-09-11 | 1972-09-11 | (2-(2-methyl-5-nitro-1-imidazolyl)ethyl)heteroaryloxy ethers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES418666A1 true ES418666A1 (en) | 1976-02-16 |
Family
ID=23105783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES418666A Expired ES418666A1 (en) | 1972-09-11 | 1973-09-11 | (2-(2-methyl-5-nitro-1-imidazolyl)ethyl)heteroaryloxy ethers |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3828056A (en) |
| JP (1) | JPS4962480A (en) |
| AR (1) | AR197526A1 (en) |
| BE (1) | BE804666A (en) |
| CA (1) | CA1006873A (en) |
| CH (1) | CH582694A5 (en) |
| DE (1) | DE2345521A1 (en) |
| DK (1) | DK135166B (en) |
| ES (1) | ES418666A1 (en) |
| FR (1) | FR2208657B1 (en) |
| GB (1) | GB1386210A (en) |
| NL (1) | NL7312458A (en) |
| ZA (1) | ZA737188B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2522176A1 (en) * | 1975-05-17 | 1976-11-25 | Hoechst Ag | 1-METHYL-2- (PYRIDYL-OXYMETHYL) -NITRO- IMIDAZOLE AND THE METHOD OF MANUFACTURING IT |
| AU5411799A (en) * | 1998-07-21 | 2000-02-14 | Syngenta Participations Ag | 3-substituted pyridine compounds and related synthesis |
| US6509471B2 (en) | 1998-07-21 | 2003-01-21 | Syngenta Participations Ag | 3-substituted pyridine compounds and related synthesis |
| CN117024351A (en) * | 2017-01-06 | 2023-11-10 | 里维斯制药股份有限公司 | Novel phenyl derivatives |
| CN111295372B (en) * | 2018-09-29 | 2021-03-09 | 江苏亚虹医药科技股份有限公司 | Nitroxoline prodrugs and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1479120A (en) * | 1965-05-10 | 1967-04-28 | Ward Blenkinsop & Co Ltd | Imidazole compounds and their preparation |
-
1972
- 1972-09-11 US US00288111A patent/US3828056A/en not_active Expired - Lifetime
-
1973
- 1973-09-10 BE BE135496A patent/BE804666A/en unknown
- 1973-09-10 DK DK496673AA patent/DK135166B/en unknown
- 1973-09-10 NL NL7312458A patent/NL7312458A/xx not_active Application Discontinuation
- 1973-09-10 CA CA180,630A patent/CA1006873A/en not_active Expired
- 1973-09-10 ZA ZA737188A patent/ZA737188B/en unknown
- 1973-09-10 DE DE19732345521 patent/DE2345521A1/en active Pending
- 1973-09-11 ES ES418666A patent/ES418666A1/en not_active Expired
- 1973-09-11 GB GB4256273A patent/GB1386210A/en not_active Expired
- 1973-09-11 AR AR250031A patent/AR197526A1/en active
- 1973-09-11 FR FR7332655A patent/FR2208657B1/fr not_active Expired
- 1973-09-11 JP JP48102571A patent/JPS4962480A/ja active Pending
- 1973-09-11 CH CH1299173A patent/CH582694A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2208657A1 (en) | 1974-06-28 |
| AR197526A1 (en) | 1974-04-15 |
| JPS4962480A (en) | 1974-06-17 |
| GB1386210A (en) | 1975-03-05 |
| BE804666A (en) | 1974-03-11 |
| US3828056A (en) | 1974-08-06 |
| DE2345521A1 (en) | 1974-03-28 |
| FR2208657B1 (en) | 1977-01-28 |
| DK135166B (en) | 1977-03-14 |
| CH582694A5 (en) | 1976-12-15 |
| DK135166C (en) | 1977-09-12 |
| ZA737188B (en) | 1974-10-30 |
| AU6014273A (en) | 1975-03-13 |
| NL7312458A (en) | 1974-03-13 |
| CA1006873A (en) | 1977-03-15 |
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