ES416907A1 - A method for producing cephalosporine preparations for employment via rectal. (Machine-translation by Google Translate, not legally binding) - Google Patents

A method for producing cephalosporine preparations for employment via rectal. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES416907A1
ES416907A1 ES416907A ES416907A ES416907A1 ES 416907 A1 ES416907 A1 ES 416907A1 ES 416907 A ES416907 A ES 416907A ES 416907 A ES416907 A ES 416907A ES 416907 A1 ES416907 A1 ES 416907A1
Authority
ES
Spain
Prior art keywords
see formula
powder
polyoxyethylene
translation
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES416907A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES416907A1 publication Critical patent/ES416907A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A method of producing cephalosporin preparations for rectal use comprising spraying powder of a cephalosporin compound of the formula **(See formula)** where R1 represents **(See formula)** R2 represents (see formula), and when R2 is (see formula), M represents a negative ion and when R2 is different from (see formula) M represents an alkali metal, to obtain a fine powder whose particle size is less than 200 microns in diameter, dry the powder of the cephalosporin compound so that the water content in the powder, and mix the finely powdered and dried powder of the cephalosporin compound (I) with an ointment or suppository base in an amount of 0.5 to 15 times by weight relative to the cephalosporin compound (I) and at least one surfactant nonionic selected from the group consisting of a polyoxyethylene-higher alcohol-ether, a polyoxyethylene-alcohol-aryl-ether and a polyoxyethylene-fatty acid ester in an amount of 0.005 to 0.5 times by weight in relation to said base, which Lipophilic Hydrophilic Balance Index (EHL) is within the range of 7 to 17. (Machine-translation by Google Translate, not legally binding)
ES416907A 1972-07-14 1973-07-13 A method for producing cephalosporine preparations for employment via rectal. (Machine-translation by Google Translate, not legally binding) Expired ES416907A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7116372A JPS4930519A (en) 1972-07-14 1972-07-14

Publications (1)

Publication Number Publication Date
ES416907A1 true ES416907A1 (en) 1976-03-16

Family

ID=13452681

Family Applications (1)

Application Number Title Priority Date Filing Date
ES416907A Expired ES416907A1 (en) 1972-07-14 1973-07-13 A method for producing cephalosporine preparations for employment via rectal. (Machine-translation by Google Translate, not legally binding)

Country Status (3)

Country Link
JP (1) JPS4930519A (en)
ES (1) ES416907A1 (en)
FR (1) FR2275214A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5336520B2 (en) * 1972-03-16 1978-10-03
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
JPS55119771U (en) * 1979-01-23 1980-08-25
JPS56104813A (en) * 1980-01-25 1981-08-20 Takeda Chem Ind Ltd Composition for rectal infusion containing compound having beta-lactam ring
EP0091502A1 (en) * 1982-04-13 1983-10-19 Asahi Kasei Kogyo Kabushiki Kaisha A pharmaceutical preparation of cephalosporin for rectal administration

Also Published As

Publication number Publication date
FR2275214B1 (en) 1978-07-28
JPS4930519A (en) 1974-03-19
FR2275214A1 (en) 1976-01-16

Similar Documents

Publication Publication Date Title
JPS5213539A (en) Preparation of aqueous dispersion of polyolefin composition
JPS56140356A (en) Dry toner
JPS51142925A (en) Address buffer circuit
JPS5241612A (en) Granular or powdered detergent compositions
ES416907A1 (en) A method for producing cephalosporine preparations for employment via rectal. (Machine-translation by Google Translate, not legally binding)
ZA802875B (en) Process for making detergent compositions
JPS5638406A (en) Manufacture of gold powder
JPS54100332A (en) Quinone compound composition and its preparation
JPS5359374A (en) Electron beam exposure unit
JPS56105844A (en) Fast-curing aqueous mold wash for use of self-hardening organic casting mold
ES372048A1 (en) Improved procedure for the obtaining of extinguishing compositions based on monoamonic orthophosphate. (Machine-translation by Google Translate, not legally binding)
JPS5283062A (en) Photoetching method
JPS51136277A (en) Lens for electron particle beam
JPS52125184A (en) Novel cephalosporin compounds
ES382188A1 (en) Procedure for the preparation of alkaline-metal soaps of fatty acid. (Machine-translation by Google Translate, not legally binding)
JPS51144430A (en) Aqueous colorant dispersion for coating
JPS5211400A (en) Chaged paticle accelerator
JPS51134899A (en) Processing method of magnetic powder
KR830010023A (en) Indeterminate refractory
JPS5213050A (en) Bearing for an air turbine
JPS527546A (en) Elevator control system
JPS57198539A (en) Magnetic recording medium
JPS53129588A (en) Electron beam exposure unit
JPS5542325A (en) Magnetic recording medium
JPS5295658A (en) Preparation of thienyl acetate derivatives