ES416766A1 - A procedure for the preparation of (3-trifluormethylphenoxy) - (4-chlorophenyl) acetate of 2-acetamidoetilo. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of (3-trifluormethylphenoxy) - (4-chlorophenyl) acetate of 2-acetamidoetilo. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES416766A1
ES416766A1 ES416766A ES416766A ES416766A1 ES 416766 A1 ES416766 A1 ES 416766A1 ES 416766 A ES416766 A ES 416766A ES 416766 A ES416766 A ES 416766A ES 416766 A1 ES416766 A1 ES 416766A1
Authority
ES
Spain
Prior art keywords
chlorophenyl
translation
acetate
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES416766A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES416766A1 publication Critical patent/ES416766A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the preparation of (3-trifluoromethylphenoxy) - (4-chlorophenyl) acetate 2-acetamidoethyl which consists in treating (3-trifluoromethylphenoxy) - (4-chlorophenyl) acetonitrile with 2-acetamidoethanol in the presence of an acid, at a temperature between about -20º and 30º c, to form the 2-acetamidoethyl (3-trifluoromethylphenoxy) - (4-chlorophenyl) iminoacetate in the form of the acid addition salt, followed by treatment with an aqueous solution. (Machine-translation by Google Translate, not legally binding)
ES416766A 1972-07-13 1973-07-10 A procedure for the preparation of (3-trifluormethylphenoxy) - (4-chlorophenyl) acetate of 2-acetamidoetilo. (Machine-translation by Google Translate, not legally binding) Expired ES416766A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27144472A 1972-07-13 1972-07-13

Publications (1)

Publication Number Publication Date
ES416766A1 true ES416766A1 (en) 1976-07-16

Family

ID=23035595

Family Applications (1)

Application Number Title Priority Date Filing Date
ES416766A Expired ES416766A1 (en) 1972-07-13 1973-07-10 A procedure for the preparation of (3-trifluormethylphenoxy) - (4-chlorophenyl) acetate of 2-acetamidoetilo. (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
JP (1) JPS4951246A (en)
DD (1) DD104505A5 (en)
ES (1) ES416766A1 (en)
HU (1) HU167339B (en)
NL (1) NL7309039A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262118B1 (en) * 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
CN1922143A (en) 2004-02-18 2007-02-28 麦它波莱克斯股份有限公司 Alpha(trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents
EP1751120A4 (en) 2004-05-25 2010-05-05 Metabolex Inc Substituted triazoles as modulators of ppar and methods of their preparation

Also Published As

Publication number Publication date
DD104505A5 (en) 1974-03-12
HU167339B (en) 1975-09-27
NL7309039A (en) 1974-01-15
JPS4951246A (en) 1974-05-18

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