ES385474A1 - Procedure for the preparation of alpha-escina by isomerization of beta-escina in aqueous solution. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of alpha-escina by isomerization of beta-escina in aqueous solution. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES385474A1
ES385474A1 ES385474A ES385474A ES385474A1 ES 385474 A1 ES385474 A1 ES 385474A1 ES 385474 A ES385474 A ES 385474A ES 385474 A ES385474 A ES 385474A ES 385474 A1 ES385474 A1 ES 385474A1
Authority
ES
Spain
Prior art keywords
escina
beta
alpha
isomerization
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES385474A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Deutschland GmbH
Original Assignee
Klinge Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691957136 external-priority patent/DE1957136C3/en
Application filed by Klinge Pharma GmbH and Co filed Critical Klinge Pharma GmbH and Co
Publication of ES385474A1 publication Critical patent/ES385474A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for the preparation of alpha-escin by isomerization of beta-escin in aqueous solution, characterized in that beta-escin is treated at a ph value within the range of 9.5 to 11.2 at room temperature, keeping this value ph optionally with addition of agents with alkaline reaction, preferably until the completion of the beta-escin reaction to form alpha-escin. (Machine-translation by Google Translate, not legally binding)
ES385474A 1969-11-13 1970-11-12 Procedure for the preparation of alpha-escina by isomerization of beta-escina in aqueous solution. (Machine-translation by Google Translate, not legally binding) Expired ES385474A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691957136 DE1957136C3 (en) 1969-11-13 Process for the isomerization of beta-ascine

Publications (1)

Publication Number Publication Date
ES385474A1 true ES385474A1 (en) 1973-05-01

Family

ID=5751006

Family Applications (1)

Application Number Title Priority Date Filing Date
ES385474A Expired ES385474A1 (en) 1969-11-13 1970-11-12 Procedure for the preparation of alpha-escina by isomerization of beta-escina in aqueous solution. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
AT (1) AT302543B (en)
BE (1) BE758819A (en)
CH (1) CH550785A (en)
ES (1) ES385474A1 (en)
FR (1) FR2073351A1 (en)
LU (1) LU62051A1 (en)
NL (1) NL7016554A (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1116890A (en) * 1967-03-23 1968-06-12 Klinge Co Chem Pharm Fab Process for the preparation of a water-soluble horse-chestnut saponin
AT274250B (en) * 1968-04-17 1969-09-10 Nattermann & Cie Arzneimittel Process for the production of water-soluble aescin from horse chestnut seeds and extracts made from them

Also Published As

Publication number Publication date
AT302543B (en) 1972-10-25
CH550785A (en) 1974-06-28
DE1957136A1 (en) 1971-05-19
FR2073351A1 (en) 1971-10-01
BE758819A (en) 1971-04-16
LU62051A1 (en) 1971-05-11
NL7016554A (en) 1971-05-17
FR2073351B1 (en) 1974-02-22

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