ES414789A1 - 3-phosphinyloxy-isothiazoles processes for their preparation and compositions incorporating them - Google Patents

Abstract

Preparation procedure for organophosphate derivatives of isothiazole, of formula I **(See formula)** wherein R1 represents a linear or branched alcohol radical containing 1 to 3 carbon atoms, an alkoxy radical containing 1 to 3 carbon atoms, or a radical -NR'R'', representing R'and R'', which are identical or different, a hydrogen atom or a linear or branched alcohol radical containing 1 to 3 carbon atoms R2 represents a linear or branched alcohol radical containing 1 to 3 carbon atoms, R' 3 represents a hydrogen atom, a linear or branched alcohol radical having 1 to 5 carbon atoms, an aryl radical containing 6 to 10 carbon atoms, an aralcohyl radical having 7 to 12 carbon atoms, a cyano radical, a carbalkoxy radical having 2 to 4 carbon atoms, or an NHR radical "", with R "" representing a hydrogen atom or an aryl radical containing 6 to 10 carbon atoms, represents a radical cyano, an alcoholylthio radical having 1 to 4 carbon atoms, an alco radical hisulfinil containing 1 to 4 carbon atoms, an alcohol sulfonyl radical containing 1 to 4 carbon atoms, a carbamoyl radical or a carbalkoxy radical containing 2 to 4 carbon atoms, or a SO2NR radical'''' R''''', representing R''''and R'''''', which may be the same or different, a hydrogen atom or an alcohol radical containing 1 to 3 carbon atoms, and X represents an atom oxygen or a sulfur atom, characterized by reacting a 3-hydroxy-isothiazole of formula II **(See formula)** or its alkali metal salt, with a halogenated phosphoric or thiophosphoric ester, of formula III **(See formula)** X, R1, R2, R3'and R4 having the meaning given above, Hal representing a chlorine or bromine atom. (Machine-translation by Google Translate, not legally binding)