ES414516A1 - Thiazole derivative - Google Patents

Thiazole derivative

Info

Publication number
ES414516A1
ES414516A1 ES414516A ES414516A ES414516A1 ES 414516 A1 ES414516 A1 ES 414516A1 ES 414516 A ES414516 A ES 414516A ES 414516 A ES414516 A ES 414516A ES 414516 A1 ES414516 A1 ES 414516A1
Authority
ES
Spain
Prior art keywords
thiazole derivative
diisopropyl
hydroxyethyl
methyl
thiazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES414516A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Publication of ES414516A1 publication Critical patent/ES414516A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/17—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C49/173—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for preparing (N, N-diisopropyl-acetamido) -3-methyl-4- (β -hydroxyethyl) -5-thiazolium bromide, which consists of reacting, in stoichiometric proportions, N, N-diisopropyl-bromoacetamide on methyl-4-hydroxyethyl-5-thiazole, in butanol, at the boil. (Machine-translation by Google Translate, not legally binding)
ES414516A 1972-05-09 1973-05-08 Thiazole derivative Expired ES414516A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2156772A GB1364779A (en) 1972-05-09 1972-05-09 Thiazole derivative

Publications (1)

Publication Number Publication Date
ES414516A1 true ES414516A1 (en) 1976-05-01

Family

ID=10165089

Family Applications (1)

Application Number Title Priority Date Filing Date
ES414516A Expired ES414516A1 (en) 1972-05-09 1973-05-08 Thiazole derivative

Country Status (11)

Country Link
JP (1) JPS5314069B2 (en)
AR (1) AR196248A1 (en)
AT (1) AT323157B (en)
AU (1) AU5476373A (en)
BE (1) BE798385A (en)
DE (1) DE2323465A1 (en)
ES (1) ES414516A1 (en)
FR (2) FR2183766B3 (en)
GB (1) GB1364779A (en)
NL (1) NL7306033A (en)
ZA (1) ZA732677B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO315930B1 (en) * 1995-01-18 2003-11-17 Picower Inst For Medical Res T Use of Thiazolium Compounds in the Preparation of Pharmaceutical Preparations, Compounds Containing the Compounds, and Nyetiazolium Compounds
DE69629176T2 (en) * 1995-01-18 2004-06-03 Alteon Inc. USE OF THIAZOLIUM COMPOUNDS TO PREVENT AND REVERSE THE END PRODUCTS OF ADVANCED GLYCOSYLATION
US5656261A (en) 1995-01-18 1997-08-12 The Picower Institute For Medical Research Preventing and reversing advanced glycosylation endproducts
US20050014747A1 (en) 2003-04-18 2005-01-20 Emily Reinhard Dihydrothiazine prodrugs of thiazolium agents

Also Published As

Publication number Publication date
BE798385A (en) 1973-10-18
NL7306033A (en) 1973-11-13
JPS4954367A (en) 1974-05-27
FR2183766B3 (en) 1976-04-23
AT323157B (en) 1975-06-25
ZA732677B (en) 1974-03-27
JPS5314069B2 (en) 1978-05-15
DE2323465A1 (en) 1973-11-22
AU5476373A (en) 1974-10-24
FR2183767A1 (en) 1973-12-21
FR2183766A1 (en) 1973-12-21
GB1364779A (en) 1974-08-29
AR196248A1 (en) 1973-12-10
FR2183767B1 (en) 1976-12-03

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