ES412453A1 - A procedure for the preparation of a composite of cefalosporine. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of a composite of cefalosporine. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES412453A1
ES412453A1 ES412453A ES412453A ES412453A1 ES 412453 A1 ES412453 A1 ES 412453A1 ES 412453 A ES412453 A ES 412453A ES 412453 A ES412453 A ES 412453A ES 412453 A1 ES412453 A1 ES 412453A1
Authority
ES
Spain
Prior art keywords
translation
preparation
machine
cephalosporin
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES412453A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of ES412453A1 publication Critical patent/ES412453A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A process for the preparation of a cephalosporin compound, comprising the steps of a) forming a penicillin 1-beta-oxide having a protective ester group in the 3-position; b) converting said δ 3-3-methyl-cephalosporin ester, and c) removing the side chain in position 7- of said cephalosporin ester, to form a corresponding ester of 7-beta-amino-cephalosporin, characterized in that the protective ester group in the 3- position of penicillin 1-beta-oxide and in the 4- position of the cephalosporin compounds is, throughout the process, a diphenylmethyl ester group. (Machine-translation by Google Translate, not legally binding)
ES412453A 1972-03-09 1973-03-08 A procedure for the preparation of a composite of cefalosporine. (Machine-translation by Google Translate, not legally binding) Expired ES412453A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1110772 1972-03-09

Publications (1)

Publication Number Publication Date
ES412453A1 true ES412453A1 (en) 1976-01-16

Family

ID=9980177

Family Applications (2)

Application Number Title Priority Date Filing Date
ES412453A Expired ES412453A1 (en) 1972-03-09 1973-03-08 A procedure for the preparation of a composite of cefalosporine. (Machine-translation by Google Translate, not legally binding)
ES433905A Expired ES433905A1 (en) 1972-03-09 1975-01-17 A procedure for the preparation of an synthetic cephalosporine antibiotic. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES433905A Expired ES433905A1 (en) 1972-03-09 1975-01-17 A procedure for the preparation of an synthetic cephalosporine antibiotic. (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
JP (1) JPS48103595A (en)
AU (1) AU5310473A (en)
BE (1) BE796458A (en)
DE (1) DE2311597A1 (en)
ES (2) ES412453A1 (en)
FR (1) FR2175169A1 (en)
NL (1) NL7303263A (en)
ZA (1) ZA731659B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953440A (en) * 1974-12-13 1976-04-27 Eli Lilly And Company Deacetoxycephalosporins via penicillin sulfoxide rearrangement
FR2356656A1 (en) * 1976-06-28 1978-01-27 Viridis Ets Prepn. of cephem-carboxylic acid antibacterial agent - by reacting cyanomethyl mercapto-acetic acid with a cephem- carboxylic acid ester
JP7335362B2 (en) 2019-06-12 2023-08-29 ヌーリオン ケミカルズ インターナショナル ベスローテン フェノーツハップ Process for producing diacyl peroxide
WO2020249688A1 (en) 2019-06-12 2020-12-17 Nouryon Chemicals International B.V. Process for the production of diacyl peroxides
ES2963356T3 (en) * 2019-06-12 2024-03-26 Nouryon Chemicals Int Bv Method for isolating carboxylic acid from an aqueous side stream

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3549628A (en) * 1967-07-07 1970-12-22 Lilly Co Eli Side chain cleavage in desacetoxycephalosporin esters

Also Published As

Publication number Publication date
JPS48103595A (en) 1973-12-25
ES433905A1 (en) 1976-11-16
FR2175169A1 (en) 1973-10-19
NL7303263A (en) 1973-09-11
AU5310473A (en) 1974-09-12
ZA731659B (en) 1974-10-30
FR2175169B1 (en) 1977-04-22
BE796458A (en) 1973-09-10
DE2311597A1 (en) 1973-09-27

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