ES411374A1 - Substituted, 6,7 ethylenedioxy 4 hydroxy 3 non oxo carbonylic quinolines - Google Patents

Substituted, 6,7 ethylenedioxy 4 hydroxy 3 non oxo carbonylic quinolines

Info

Publication number
ES411374A1
ES411374A1 ES411374A ES411374A ES411374A1 ES 411374 A1 ES411374 A1 ES 411374A1 ES 411374 A ES411374 A ES 411374A ES 411374 A ES411374 A ES 411374A ES 411374 A1 ES411374 A1 ES 411374A1
Authority
ES
Spain
Prior art keywords
carbonylic
quinolines
ethylenedioxy
hydroxy
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES411374A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Philips Gloeilampenfabrieken NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL7201675A external-priority patent/NL7201675A/xx
Priority claimed from NL7215366A external-priority patent/NL7215366A/en
Application filed by Philips Gloeilampenfabrieken NV filed Critical Philips Gloeilampenfabrieken NV
Publication of ES411374A1 publication Critical patent/ES411374A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Compounds of the formula 1 have potent diuretic and saluretic effects and a very low toxicity. The compounds can be synthesized by usual methods and be given suitable forms for administration and be used for the treatment of inter alia edemas. The compounds are novel.
ES411374A 1972-02-09 1973-02-07 Substituted, 6,7 ethylenedioxy 4 hydroxy 3 non oxo carbonylic quinolines Expired ES411374A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7201675A NL7201675A (en) 1972-02-09 1972-02-09
NL7215366A NL7215366A (en) 1972-11-14 1972-11-14 P-dioxino(2,3-g)quinolines - diuretics, saluretics and hypotensives

Publications (1)

Publication Number Publication Date
ES411374A1 true ES411374A1 (en) 1976-07-01

Family

ID=26644729

Family Applications (1)

Application Number Title Priority Date Filing Date
ES411374A Expired ES411374A1 (en) 1972-02-09 1973-02-07 Substituted, 6,7 ethylenedioxy 4 hydroxy 3 non oxo carbonylic quinolines

Country Status (16)

Country Link
US (1) US3865832A (en)
JP (1) JPS5727112B2 (en)
AR (1) AR211510A1 (en)
AT (1) AT323740B (en)
BE (1) BE795265A (en)
CA (1) CA1000279A (en)
CH (1) CH593285A5 (en)
DE (1) DE2303496A1 (en)
DK (1) DK138120B (en)
ES (1) ES411374A1 (en)
FI (1) FI55847C (en)
FR (1) FR2181708B1 (en)
GB (1) GB1366834A (en)
IL (1) IL41471A (en)
PH (1) PH14448A (en)
SE (1) SE416467B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036962A (en) * 1974-08-12 1977-07-19 E. I. Du Pont De Nemours And Co. 6,7-Methylenedioxy-1-(2,2,2-trifluoroethyl)-4(1H)-quinolone-3-carboxylic acid and its salts and esters
US4179506A (en) * 1978-11-13 1979-12-18 Warner-Lambert Company New pyridobenzodioxin compounds and methods for their production
FR2846327B1 (en) * 2002-10-25 2006-03-24 Merck Sante Sas N-BENZODIOXOLYL, N-BENZODIOXANYL AND N-BENZODIOXEPINYL ARYLCARBOXAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF DYSLIPIDEMIA AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
BRPI1013579A2 (en) * 2009-03-30 2020-11-03 Transtech Pharma, Inc. substituted azoanthracene derivatives, pharmaceutical compositions and methods of using them
CN113717185B (en) * 2021-08-19 2023-04-11 云南省烟草农业科学研究院 Quinoline alkaloid compound with antibacterial activity in cigar rhizome and preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3178348A (en) * 1961-02-08 1965-04-13 Norwich Pharma Co Hypotensive quinolines
GB1076828A (en) * 1963-12-12 1967-07-26 Warner Lambert Pharmaceutical Methylenedioxy quinoline derivatives
DE1908548A1 (en) * 1968-02-29 1970-11-05 Warner Lambert Co Quinoline derivatives
CA942310A (en) * 1969-07-09 1974-02-19 Mitsuo Nakashita Preparation of n-substituted 6,7-methylenedioxy-4-quinolone derivatives
DE2030899A1 (en) * 1970-06-18 1971-12-23 Schering Ag, 1000 Berlin Und 4619 Bergkamen Quinoline carboxylic acid derivatives

Also Published As

Publication number Publication date
AR211510A1 (en) 1978-01-30
FR2181708A1 (en) 1973-12-07
FI55847C (en) 1979-10-10
CH593285A5 (en) 1977-11-30
SE416467B (en) 1981-01-05
CA1000279A (en) 1976-11-23
DK138120B (en) 1978-07-17
AT323740B (en) 1975-07-25
DE2303496A1 (en) 1973-08-23
FI55847B (en) 1979-06-29
GB1366834A (en) 1974-09-11
DK138120C (en) 1978-12-04
BE795265A (en) 1973-08-09
US3865832A (en) 1975-02-11
FR2181708B1 (en) 1975-10-10
PH14448A (en) 1981-07-23
JPS4886896A (en) 1973-11-15
JPS5727112B2 (en) 1982-06-08
IL41471A (en) 1975-12-31
IL41471A0 (en) 1973-04-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19840206