ES410151A1 - A procedure for preparing 2- (6-metoxy-2-nafthy) propionic acid. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for preparing 2- (6-metoxy-2-nafthy) propionic acid. (Machine-translation by Google Translate, not legally binding)
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Roche Palo Alto LLC
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Roche Palo Alto LLC
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Publication of ES410151A1publicationCriticalpatent/ES410151A1/en
C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
C07C59/40—Unsaturated compounds
C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
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Chemical & Material Sciences
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Organic Chemistry
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Organic Low-Molecular-Weight Compounds And Preparation Thereof
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Abstract
A process for preparing 2- (6-methoxy-2-naphthyl) propionic acid consisting of: A) treating a 2- (5-halo-6-methoxy-2-naphthyl) propionic acid, either as a racemic mixture or as a separate d-isomer, with a nickel-aluminum or cobalt-aluminum alloy in an aqueous solvent in the presence of of an alkali metal hydroxide, at a temperature of at least 0ºC until the reduction of the 5-halo group occurs, the 5-halo group being a chlorine, bromine or iodine; B) acidifying the reaction mixture and removing 2- (6-methoxy-2-naphthyl) propionic acid and C) resolving the racemic mixture to obtain d 2- (6-methoxy-2-naphthyl) propionic acid. (Machine-translation by Google Translate, not legally binding)
ES410151A1969-09-301972-12-29A procedure for preparing 2- (6-metoxy-2-nafthy) propionic acid. (Machine-translation by Google Translate, not legally binding)
ExpiredES410151A1
(en)
A process for the preparation of acids 2- (6-metoxy2'naftil) propionico and 2- (6-metoxy-2-naftil) -1-propanol. (Machine-translation by Google Translate, not legally binding)