ES405932A1 - Procedimiento para la preparacion de nuevos derivados de biguanida. - Google Patents
Procedimiento para la preparacion de nuevos derivados de biguanida.Info
- Publication number
- ES405932A1 ES405932A1 ES405932A ES405932A ES405932A1 ES 405932 A1 ES405932 A1 ES 405932A1 ES 405932 A ES405932 A ES 405932A ES 405932 A ES405932 A ES 405932A ES 405932 A1 ES405932 A1 ES 405932A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- formula
- alkyl
- see formula
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940123208 Biguanide Drugs 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000004283 biguanides Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000006682 monohaloalkyl group Chemical group 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 150000004866 oxadiazoles Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000006684 polyhaloalkyl group Polymers 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3923471 | 1971-08-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES405932A1 true ES405932A1 (es) | 1976-01-16 |
Family
ID=10408432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES405932A Expired ES405932A1 (es) | 1971-08-20 | 1972-08-18 | Procedimiento para la preparacion de nuevos derivados de biguanida. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3808224A (OSRAM) |
| JP (1) | JPS4829773A (OSRAM) |
| AT (1) | AT317919B (OSRAM) |
| AU (1) | AU461429B2 (OSRAM) |
| BE (1) | BE787327A (OSRAM) |
| CA (1) | CA990291A (OSRAM) |
| DE (1) | DE2240887A1 (OSRAM) |
| ES (1) | ES405932A1 (OSRAM) |
| FR (1) | FR2230347B1 (OSRAM) |
| GB (1) | GB1351025A (OSRAM) |
| NL (1) | NL7211374A (OSRAM) |
| ZA (1) | ZA725619B (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1485315A (en) * | 1975-01-16 | 1977-09-08 | Aron Soc Nouv Exploit Lab | Biguanides process for their preparation and applications thereof |
| US4103010A (en) * | 1975-01-16 | 1978-07-25 | Aron S.A.R.L. | (3-Piperazinocarbonylimino-quanidino)-isoxazoles |
| US4315009A (en) | 1978-01-18 | 1982-02-09 | Imperial Chemical Industries Limited | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| ATE852T1 (de) * | 1978-05-24 | 1982-04-15 | Imperial Chemical Industries Plc | Anti-sekretion oxadiazol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
| DK185389A (da) * | 1988-04-22 | 1989-10-23 | Duphar Int Res | 3,5-substituerede 1,2,4-oxadiazoler, deres fremstiling og anvendelse |
| DE19755016A1 (de) * | 1997-12-11 | 1999-06-17 | Bayer Ag | Substituierte 2,4-Diamino-1,3,5-triazine |
| ZA9811445B (en) | 1997-12-19 | 1999-08-16 | Alcon Lab Inc | Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions. |
| FR2809310B1 (fr) | 2000-05-26 | 2004-02-13 | Centre Nat Rech Scient | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
| US6936640B2 (en) * | 2003-12-04 | 2005-08-30 | Alcon, Inc. | Biguanide/quaternary ammonium containing copolymeric biocides and use thereof in pharmaceutical compositions |
| CN102316872B (zh) * | 2008-11-26 | 2016-12-21 | 萨蒂奥根制药公司 | 治疗肥胖症和糖尿病的胆汁酸再循环抑制剂 |
| CN111320617A (zh) * | 2018-12-17 | 2020-06-23 | 华中科技大学 | 苯基噁二唑类衍生物及其制备方法与应用 |
-
1971
- 1971-08-20 GB GB3923471A patent/GB1351025A/en not_active Expired
-
1972
- 1972-08-04 FR FR7228279A patent/FR2230347B1/fr not_active Expired
- 1972-08-08 BE BE787327A patent/BE787327A/xx unknown
- 1972-08-11 US US00282194A patent/US3808224A/en not_active Expired - Lifetime
- 1972-08-15 CA CA149,783A patent/CA990291A/en not_active Expired
- 1972-08-15 ZA ZA725619A patent/ZA725619B/xx unknown
- 1972-08-17 AU AU45720/72A patent/AU461429B2/en not_active Expired
- 1972-08-18 NL NL7211374A patent/NL7211374A/xx unknown
- 1972-08-18 AT AT717272A patent/AT317919B/de not_active IP Right Cessation
- 1972-08-18 ES ES405932A patent/ES405932A1/es not_active Expired
- 1972-08-19 JP JP47083247A patent/JPS4829773A/ja active Pending
- 1972-08-19 DE DE2240887A patent/DE2240887A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU4572072A (en) | 1974-02-21 |
| US3808224A (en) | 1974-04-30 |
| AT317919B (de) | 1974-09-25 |
| GB1351025A (en) | 1974-04-24 |
| BE787327A (fr) | 1972-12-01 |
| AU461429B2 (en) | 1975-05-29 |
| NL7211374A (OSRAM) | 1973-02-22 |
| ZA725619B (en) | 1973-05-30 |
| CA990291A (en) | 1976-06-01 |
| JPS4829773A (OSRAM) | 1973-04-19 |
| FR2230347B1 (OSRAM) | 1976-08-20 |
| FR2230347A1 (OSRAM) | 1974-12-20 |
| DE2240887A1 (de) | 1973-03-01 |
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