ES397552A1 - Un procedimiento para la preparacion de monoclorhidrado de 7 - cloro - 1 - (2-dietilaminoetil) - 5 - (2 - fluorofenil) 1,3-dihidro - 2h - 1,4 - benzodiacepin - 2-ona. - Google Patents
Un procedimiento para la preparacion de monoclorhidrado de 7 - cloro - 1 - (2-dietilaminoetil) - 5 - (2 - fluorofenil) 1,3-dihidro - 2h - 1,4 - benzodiacepin - 2-ona.Info
- Publication number
- ES397552A1 ES397552A1 ES397552A ES397552A ES397552A1 ES 397552 A1 ES397552 A1 ES 397552A1 ES 397552 A ES397552 A ES 397552A ES 397552 A ES397552 A ES 397552A ES 397552 A1 ES397552 A1 ES 397552A1
- Authority
- ES
- Spain
- Prior art keywords
- benzodiazepine
- diethylaminoethyl
- fluorophenyl
- dihydro
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- -1 2-diethylaminoethyl Chemical group 0.000 abstract 1
- 125000004198 2-fluorophenyl group Chemical group [H]C1=C([H])C(F)=C(*)C([H])=C1[H] 0.000 abstract 1
- PUGVROXLRUQCAF-UHFFFAOYSA-N Flurazepam monohydrochloride Chemical compound Cl.N=1CC(=O)N(CCN(CC)CC)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1F PUGVROXLRUQCAF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- SAADBVWGJQAEFS-UHFFFAOYSA-N flurazepam Chemical compound N=1CC(=O)N(CCN(CC)CC)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1F SAADBVWGJQAEFS-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH832571A CH553792A (de) | 1971-06-08 | 1971-06-08 | Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES397552A1 true ES397552A1 (es) | 1975-03-16 |
Family
ID=4338591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES397552A Expired ES397552A1 (es) | 1971-06-08 | 1971-02-01 | Un procedimiento para la preparacion de monoclorhidrado de 7 - cloro - 1 - (2-dietilaminoetil) - 5 - (2 - fluorofenil) 1,3-dihidro - 2h - 1,4 - benzodiacepin - 2-ona. |
Country Status (31)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1199304A1 (en) * | 1997-03-05 | 2002-04-24 | Takeda Chemical Industries, Ltd. | Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders |
-
1971
- 1971-02-01 ES ES397552A patent/ES397552A1/es not_active Expired
- 1971-06-08 CH CH832571A patent/CH553792A/xx not_active IP Right Cessation
- 1971-11-15 FI FI713268A patent/FI51352C/fi active
- 1971-11-15 NO NO4214/71A patent/NO133714C/no unknown
- 1971-11-16 SE SE7114654A patent/SE388856B/xx unknown
- 1971-11-16 DK DK561771AA patent/DK127506B/da not_active IP Right Cessation
- 1971-11-17 HU HUHO1433A patent/HU170152B/hu unknown
- 1971-11-17 DE DE2157112A patent/DE2157112C3/de not_active Expired
- 1971-11-18 AT AT996671A patent/AT313281B/de not_active IP Right Cessation
- 1971-11-22 PL PL1971151697A patent/PL81437B1/pl unknown
- 1971-11-23 ZA ZA717880A patent/ZA717880B/xx unknown
- 1971-11-23 CA CA128,336A patent/CA945989A/en not_active Expired
- 1971-11-23 GB GB5436871A patent/GB1331823A/en not_active Expired
- 1971-11-23 CY CY868A patent/CY868A/xx unknown
- 1971-11-24 IE IE1489/71A patent/IE35846B1/xx unknown
- 1971-11-25 BG BG019094A patent/BG19173A3/xx unknown
- 1971-11-29 IL IL38252A patent/IL38252A/xx unknown
- 1971-11-29 NL NL7116376A patent/NL7116376A/xx unknown
- 1971-11-29 SU SU1721027A patent/SU444369A3/ru active
- 1971-11-29 SU SU1959119A patent/SU475776A3/ru active
- 1971-12-02 RO RO68930A patent/RO59000A/ro unknown
- 1971-12-02 JP JP46096838A patent/JPS5230568B1/ja active Pending
- 1971-12-02 RO RO75458A patent/RO58965A/ro unknown
- 1971-12-04 MX MX131834A patent/MX149567A/es unknown
- 1971-12-08 BR BR8123/71A patent/BR7108123D0/pt unknown
- 1971-12-09 PH PH13088A patent/PH13530A/en unknown
- 1971-12-29 DD DD159994A patent/DD98679A5/xx unknown
- 1971-12-30 CS CS752472A patent/CS155106B2/cs unknown
- 1971-12-30 CS CS913171A patent/CS155105B2/cs unknown
-
1972
- 1972-01-11 FR FR7200802A patent/FR2140371B1/fr not_active Expired
- 1972-01-11 BE BE777897A patent/BE777897A/xx not_active IP Right Cessation
- 1972-06-06 LU LU65469A patent/LU65469A1/xx unknown
-
1974
- 1974-12-30 MY MY115/74A patent/MY7400115A/xx unknown
-
1975
- 1975-11-20 SE SE7513088A patent/SE7513088L/xx unknown
-
1976
- 1976-07-21 KE KE2652*UA patent/KE2652A/xx unknown
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