ES394988A1 - Procedure for the preparation of nitrofuran derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of nitrofuran derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES394988A1
ES394988A1 ES394988A ES394988A ES394988A1 ES 394988 A1 ES394988 A1 ES 394988A1 ES 394988 A ES394988 A ES 394988A ES 394988 A ES394988 A ES 394988A ES 394988 A1 ES394988 A1 ES 394988A1
Authority
ES
Spain
Prior art keywords
group
general formula
formula
carbon atoms
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES394988A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702045049 external-priority patent/DE2045049A1/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES394988A1 publication Critical patent/ES394988A1/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Procedure for the preparation of nitrofuran derivatives of the general formula I **(See formula)** wherein R1 signifies a hydrogen atom, a straight-chain or branched alcohol group with 1 to 6 carbon atoms, which may optionally be substituted by a hydroxyl group, or the group (see formula), in which the radicals R7 and R8 represent a straight or branched chain alcohol group with 1 to 4 carbon atoms or together with the nitrogen atom located between them represent the morpholino, pyrrolidino, piperidino or N- radical methylpiperazine; R2 means a hydrogen atom or an alcohol group with 1 to 3 carbon atoms; R3 means a hydrogen atom or a straight-chain or branched alcohol group with 1 to 5 carbon atoms, which may optionally be substituted by a hydroxyl group; X means an oxygen atom, the imino group or the methylimino group, Y means an oxygen or sulfur atom or the imino group, and n means the numbers 0 or 1 and, if basic nitrogen atoms are present, their salts with inorganic or organic acids, characterized in that a compound of the general formula II is reacted **(See formula)** wherein X has the aforementioned meanings and the radicals R4 and R5 and signifies alcoholic groups or together an alcoholic group, which joins the two sulfur atoms, with an amine of the general formula III **(See formula)** in which Y, n, R1, R2 and R3 have the aforementioned meanings at temperatures between 20 and 150ºC, the intermediate compound, which appears in this case, of the general formula IV being optionally isolated **(See formula)** wherein the radicals R1, R2, R3, R5, X and Y and n are as initially defined, and are then cyclized by heating at temperatures between 100 and 200ºC to form the compound of formula I and, in case of In accordance with this procedure, a compound of the general formula I having a basic nitrogen atom results, which is subsequently transformed into its salts by means of organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
ES394988A 1970-09-11 1971-09-10 Procedure for the preparation of nitrofuran derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES394988A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19702045049 DE2045049A1 (en) 1970-09-11 1970-09-11 New Nitrofurandenvate and processes for their production
DE19712127735 DE2127735A1 (en) 1970-09-11 1971-06-04 Process for the production of nitrofuan derivatives

Publications (1)

Publication Number Publication Date
ES394988A1 true ES394988A1 (en) 1974-03-16

Family

ID=25759713

Family Applications (2)

Application Number Title Priority Date Filing Date
ES394988A Expired ES394988A1 (en) 1970-09-11 1971-09-10 Procedure for the preparation of nitrofuran derivatives. (Machine-translation by Google Translate, not legally binding)
ES394989A Expired ES394989A1 (en) 1970-09-11 1971-09-10 Procedure for the preparation of nitrofuran derivatives. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES394989A Expired ES394989A1 (en) 1970-09-11 1971-09-10 Procedure for the preparation of nitrofuran derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (2) ES394988A1 (en)

Also Published As

Publication number Publication date
ES394989A1 (en) 1974-03-16

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