ES393566A1 - Un procedimiento para preparar derivados de 1,4 benzodiaze-pina 7-nitro-sustituidos. - Google Patents
Un procedimiento para preparar derivados de 1,4 benzodiaze-pina 7-nitro-sustituidos.Info
- Publication number
- ES393566A1 ES393566A1 ES393566A ES393566A ES393566A1 ES 393566 A1 ES393566 A1 ES 393566A1 ES 393566 A ES393566 A ES 393566A ES 393566 A ES393566 A ES 393566A ES 393566 A1 ES393566 A1 ES 393566A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- compound
- same meanings
- nitro
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GUJAGMICFDYKNR-UHFFFAOYSA-N 1,4-benzodiazepine Chemical class N1C=CN=CC2=CC=CC=C12 GUJAGMICFDYKNR-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 7-nitro-substituted 1,4-benzodiazepine Chemical class 0.000 abstract 1
- IKRUYQSSMVEDKZ-UHFFFAOYSA-N C1(CC=CC=C1)C1NCC(NC2=C1C=C(C=C2)N)=O Chemical compound C1(CC=CC=C1)C1NCC(NC2=C1C=C(C=C2)N)=O IKRUYQSSMVEDKZ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 238000010306 acid treatment Methods 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001371 alpha-amino acids Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 abstract 1
- HSDAJNMJOMSNEV-UHFFFAOYSA-N benzyl chloroformate Chemical compound ClC(=O)OCC1=CC=CC=C1 HSDAJNMJOMSNEV-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI000404 | 1970-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES393566A1 true ES393566A1 (es) | 1973-08-16 |
Family
ID=11000847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES393566A Expired ES393566A1 (es) | 1970-07-30 | 1971-07-23 | Un procedimiento para preparar derivados de 1,4 benzodiaze-pina 7-nitro-sustituidos. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5510588B1 (enrdf_load_stackoverflow) |
| AT (1) | AT317893B (enrdf_load_stackoverflow) |
| CH (1) | CH556851A (enrdf_load_stackoverflow) |
| CS (1) | CS171709B2 (enrdf_load_stackoverflow) |
| ES (1) | ES393566A1 (enrdf_load_stackoverflow) |
| NL (1) | NL7110495A (enrdf_load_stackoverflow) |
| PL (1) | PL77754B1 (enrdf_load_stackoverflow) |
| SE (1) | SE387942B (enrdf_load_stackoverflow) |
| SU (1) | SU650505A3 (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU171033B (hu) * | 1974-05-29 | 1977-10-28 | Richter Gedeon Vegyeszet | Sposob poluchenija proizvodnykh benzodiazepina |
| RU2150467C1 (ru) * | 1998-01-06 | 2000-06-10 | Петрунин Александр Иванович | Способ получения 1,3-дигидро-7-нитро-5-фенил-2h-1,4-бензодиазепин-2-она (нитразепама) (варианты) |
-
1971
- 1971-07-20 CH CH1068771A patent/CH556851A/de not_active IP Right Cessation
- 1971-07-22 AT AT636171A patent/AT317893B/de not_active IP Right Cessation
- 1971-07-23 ES ES393566A patent/ES393566A1/es not_active Expired
- 1971-07-26 CS CS5454A patent/CS171709B2/cs unknown
- 1971-07-27 JP JP5574271A patent/JPS5510588B1/ja active Pending
- 1971-07-28 PL PL1971149702A patent/PL77754B1/pl unknown
- 1971-07-28 SE SE7109700A patent/SE387942B/xx unknown
- 1971-07-29 SU SU711688511A patent/SU650505A3/ru active
- 1971-07-29 NL NL7110495A patent/NL7110495A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT317893B (de) | 1974-09-25 |
| NL7110495A (enrdf_load_stackoverflow) | 1972-02-01 |
| CS171709B2 (enrdf_load_stackoverflow) | 1976-10-29 |
| CH556851A (de) | 1974-12-13 |
| PL77754B1 (enrdf_load_stackoverflow) | 1975-04-30 |
| SU650505A3 (ru) | 1979-02-28 |
| JPS5510588B1 (enrdf_load_stackoverflow) | 1980-03-17 |
| SE387942B (sv) | 1976-09-20 |
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