ES390456A1 - 17alpha-propadienyl steroids - Google Patents

17alpha-propadienyl steroids

Info

Publication number
ES390456A1
ES390456A1 ES390456A ES390456A ES390456A1 ES 390456 A1 ES390456 A1 ES 390456A1 ES 390456 A ES390456 A ES 390456A ES 390456 A ES390456 A ES 390456A ES 390456 A1 ES390456 A1 ES 390456A1
Authority
ES
Spain
Prior art keywords
formula
17alpha
compound
propadienyl
steroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES390456A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES390456A1 publication Critical patent/ES390456A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)

Abstract

Procedure for obtaining 13-alkyl-17β-hydroxy-17α-propadienylgon-4,9 (10), 11-trien-3-one, of formula I, ** (See formula) ** wherein R is a methyl, ethyl or n-propyl radical, characterized in that a compound of formula-II is treated, where R has the meaning indicated above, with a compound of formula X, ** (See formula) ** wherein each of Z, Z1, Z2 and Z3, which may be the same or different, signifies a chlorine or bromine atom or a cyano radical, in an inert organic solvent. (Machine-translation by Google Translate, not legally binding)
ES390456A 1970-04-24 1971-04-22 17alpha-propadienyl steroids Expired ES390456A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3178270A 1970-04-24 1970-04-24

Publications (1)

Publication Number Publication Date
ES390456A1 true ES390456A1 (en) 1974-07-01

Family

ID=21861362

Family Applications (1)

Application Number Title Priority Date Filing Date
ES390456A Expired ES390456A1 (en) 1970-04-24 1971-04-22 17alpha-propadienyl steroids

Country Status (11)

Country Link
AT (1) ATA353071A (en)
AU (1) AU2810571A (en)
BE (1) BE766148A (en)
CA (1) CA945141A (en)
CS (1) CS155974B2 (en)
DE (1) DE2119328A1 (en)
ES (1) ES390456A1 (en)
FR (1) FR2092083B1 (en)
GB (1) GB1348186A (en)
NL (1) NL7105446A (en)
ZA (2) ZA712601B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL127071C (en) * 1964-12-31
IL34228A (en) * 1969-04-18 1975-04-25 Syntex Corp The preparation of 17alpha-propadienyl steroids and novel 17alpha-(3-substituted propynyl)steroidal intermediates

Also Published As

Publication number Publication date
NL7105446A (en) 1971-10-26
GB1348186A (en) 1974-03-13
ATA353071A (en) 1975-02-15
FR2092083B1 (en) 1974-08-23
ZA712643B (en) 1972-11-29
ZA712601B (en) 1972-11-29
CS155974B2 (en) 1974-06-24
BE766148A (en) 1971-10-22
FR2092083A1 (en) 1972-01-21
AU2810571A (en) 1972-10-26
CA945141A (en) 1974-04-09
DE2119328A1 (en) 1971-11-11

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